Pikamilone

Pikamilone
  • CAS No.:34562-97-5
Other grades of this product :
Pikamilone Basic information
Description Clinical Use
Product Name:Pikamilone
Synonyms:4-((Pyridine-3-carbonyl)-amino)-butyric acid;Pikamiline;PikamiloneHCl;3-[(3-Carboxypropyl)carbamoyl]pyridine;PIKAMILON;4-Nicotinoylamino-butylric acid;PIKAMILONE HYDROCHLORIDE;NICOTINOYL-GABA
CAS:34562-97-5
MF:C10H12N2O3
MW:208.21
EINECS:1308068-626-2
Product Categories:Other APIs;API;Heterocycles;Chemistry
Mol File:34562-97-5.mol
Pikamilone Chemical Properties
Melting point 211.0 to 215.0 °C
Boiling point 522.4±30.0 °C(Predicted)
density 1.245
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
pka4.60±0.10(Predicted)
color White to Off-White
CAS DataBase Reference34562-97-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
Pikamilone Usage And Synthesis
DescriptionPikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.
Clinical UsePikamilone treatment of benign prostatic hyperplasiaPikamilone is an original drug of Russian produce having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action. The drug was tried as monotherapy in elderly patients with benign prostatic hyperplasia who had symptoms of the lower urinary tracts to estimate its effect on local and general mechanisms of nervous and vascular regulation of detruzor function in infravesical obstruction. https://pubmed.ncbi.nlm.nih.gov/11150159/
Usesanti-cancer agent
UsesNicotinoyl-γ-aminobutyric Acid is a pro-drug of γ-Aminobutyric Acid (A602920). Studies show that Nicotinoyl-γ-aminobutyric Acid is involved in the regulation of the processes in the brain of streptozotocin-induced diabetic rats.

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