Other grades of this product :
| 2-Iodophenol Basic information |
| 2-Iodophenol Chemical Properties |
| Melting point | 37-40 °C (lit.) | | Boiling point | 186-187 °C/160 mmHg (lit.) | | density | 1.947 g/mL at 25 °C (lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Crystalline Powder or Crystalline Low Melting Mass | | pka | 8.51(at 25℃) | | Specific Gravity | 1.947 | | color | White or cream to brown | | Water Solubility | slightly soluble | | Sensitive | Light Sensitive | | Merck | 14,5035 | | BRN | 1855300 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | KQDJTBPASNJQFQ-UHFFFAOYSA-N | | CAS DataBase Reference | 533-58-4(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 2-iodo-(533-58-4) | | EPA Substance Registry System | Phenol, 2-iodo- (533-58-4) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | RTECS | SL5500000 | | TSCA | T | | HazardClass | IRRITANT, LIGHT SENSITIVE | | HS Code | 29081000 |
| 2-Iodophenol Usage And Synthesis |
| Chemical Properties | colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether. | | Uses | 2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield. | | Application | 2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity3,3-disubstituted-2,3-dihydrobenzofurans1,3,5-substituted benzenes.2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction. | | Preparation | synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 53, p. 5281, 1988 DOI: 10.1021/jo00257a014 | | General Description | Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)6 as the CO source has been investigated. | | Purification Methods | Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.] |
| 2-Iodophenol Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye