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| (2-PHENOXY)METHYLSULFONYLANILINE Basic information |
| Product Name: | (2-PHENOXY)METHYLSULFONYLANILINE | | Synonyms: | 2-PHENOXYMETHANESULFOANILIDE;2-PHENOXYMETHANESULFONANILIDE;Nimesulide EP Impurity B,(N-（2-phenoxyphenyl)methanesulfonamide);(2-PHENOXY)METHYLSULFONYLANILINE;N-(2-phenoxyphenyl)methanesulphonamide;2-Phenoxymethanesulfonailide;Einecs 257-399-1;Nimesulide impurity-B(EP/BP) | | CAS: | 51765-51-6 | | MF: | C13H13NO3S | | MW: | 263.31 | | EINECS: | 257-399-1 | | Product Categories: | | Mol File: | 51765-51-6.mol |
| (2-PHENOXY)METHYLSULFONYLANILINE Chemical Properties |
| Melting point | 126℃ | | Boiling point | 378.9±44.0 °C(Predicted) | | density | 1.313 | | vapor pressure | 0Pa at 25℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform (Slightly), DMSO | | form | Solid | | pka | 8.43±0.10(Predicted) | | color | White to Off-White | | Water Solubility | 176.1mg/L at 25℃ | | LogP | 2.4 at 25℃ |
| (2-PHENOXY)METHYLSULFONYLANILINE Usage And Synthesis |
| Uses | 2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production. |
| (2-PHENOXY)METHYLSULFONYLANILINE Preparation Products And Raw materials |
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