toddalolactone

toddalolactone
  • CAS No.:483-90-9
Other grades of this product :
toddalolactone Basic information
Product Name:toddalolactone
Synonyms:toddalolactone;6-(2,3-Dihydroxy-3-methylbutyl)-5,7-dimethoxy-2H-1-benzopyran-2-one;Toddaline;(+)-Toddalolactone;6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-chromen-2-one;6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one;6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-coumarin;Toddaloactone
CAS:483-90-9
MF:C16H20O6
MW:308.33
EINECS:
Product Categories:
Mol File:483-90-9.mol
toddalolactone Chemical Properties
Melting point 269-270°C
Boiling point 530.0±50.0 °C(Predicted)
density 1.269±0.06 g/cm3(Predicted)
pka14.39±0.20(Predicted)
Safety Information
MSDS Information
toddalolactone Usage And Synthesis
DescriptionToddalia aculeata Pers. (Rutaceae) contains, in addition to Berberine (q.v.), two closely related alkaloids. This particular base forms colourless crystals from CHC13 and is characterized as the hydrochloride monohydrate, m.p. 205-6°C; nitrate, yellow needles, m.p. 239° C (dec.) and the picrate, glancing needles, m.p. 237-8°C. Two methoxyl groups and a methylimino group have been shown to be present.
UsesToddalolactone is a prenylated coumarin which acts as a natural phosphodiesterase-4 inhibitor. Antiplasmodial and larvicidal agent.
ReferencesDey, Pillay., Arch. Pharm., 271,477 (1933)Dey et al., Ind. J. Med. Res., 22,765 (1935) Lobstein, Hesse., Bull. Sci. Pharmacol., 38, 157 (1931)
toddalolactone Preparation Products And Raw materials

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