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| Reboxetine mesylate Basic information |
| Product Name: | Reboxetine mesylate | | Synonyms: | (R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine;(R)-2-((S)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholine;REBOXETINE(FORR&DONLY);REBOXETIN;(2R)-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate;(2R*)-2-[(alphaR*)-alpha-(o-Ethoxyphenoxy)benzyl]morpholine mesylate;Reboxetine mesylate;Zinc00002275 | | CAS: | 71620-89-8 | | MF: | C19H23NO3 | | MW: | 313.4 | | EINECS: | 1592732-453-0 | | Product Categories: | Inhibitors;Adrenoceptors;Adrenoceptor;APIs;Inhibitor | | Mol File: | 71620-89-8.mol |
| Reboxetine mesylate Chemical Properties |
| Melting point | 136-139 °C | | Boiling point | 443.7±30.0 °C(Predicted) | | density | 1.113±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at +4°C | | solubility | Chloroform (Slightly), Water (Slightly) | | form | Solid | | pka | 8.37±0.40(Predicted) | | color | Off-White to Pale Beige | | CAS DataBase Reference | 71620-89-8(CAS DataBase Reference) |
| Reboxetine mesylate Usage And Synthesis |
| Uses | Antidepressant (selective noradrenaline reuptake inhibitor). | | Uses | Reboxetine can be used in biological study of the involvement of monoaminergic neurotransmission in the antidepressant-like action of scopolamine in the tail suspension test. | | Brand name | Edronax (Pharmacia & Upjohn). | | Biological Activity | Potent and selective inhibitor of noradrenalin uptake (K i values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α -adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active, clinically used antidepressant. |
| Reboxetine mesylate Preparation Products And Raw materials |
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