(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE

CAS No.：132883-44-4

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE Basic information

Product Name:	(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE
Synonyms:	(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE 96+%;DIMETHYL-PYRROLIDIN-3-YL-AMINE (S);(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE;(3S)-3-DIMETHYLAMINOPYRROLIDINE;(3S)-DIMETHYL-PYRROLIDIN-3-YL-AMINE;(3S)-N,N-DIMETHYL-3-PYRROLIDINAMINE;(S)-DIMETHYL-PYRROLIDIN-3-YL-AMINE;(S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE
CAS:	132883-44-4
MF:	C6H14N2
MW:	114.19
EINECS:
Product Categories:	3-Aminopyrrolidines;Amines (Chiral);chiral;Chiral 3-Aminopyrrolidines;Chiral Building Blocks;Synthetic Organic Chemistry
Mol File:	132883-44-4.mol

(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE Chemical Properties

Boiling point	160 °C/760 mmHg (lit.)
density	0.899 g/mL at 25 °C (lit.)
refractive index	n20/D1.4650(lit.)
Fp	125 °F
storage temp.	2-8°C
pka	9.93±0.10(Predicted)
form	clear liquid
color	Colorless to Light yellow
Specific Gravity	0.90
optical activity	[α]/D 14±2°, c = 1 in ethanol
CAS DataBase Reference	132883-44-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	10-22-37/38-41-38-37
Safety Statements	26-39
RIDADR	UN 1993 3/PG 3
WGK Germany	2
HazardClass	3
PackingGroup	III
HS Code	2933998090

MSDS Information

Provider	Language
SigmaAldrich	English

(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	(S)-(?)-3-(Dimethylamino)pyrrolidine can be used as a reactant in the syntheses of oxadiazolylthiazole and xanthone derivatives of biological importance.

(3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE Preparation Products And Raw materials

Raw materials

Ethanol-->Hydrochloric acid-->Dichloromethane-->Potassium carbonate-->Triethylamine-->Pyridine-->Palladium-->Tosyl chloride-->(S)-1-Benzyl-3-pyrrolidinol-->(R)-(+)-1-Benzyl-3-pyrrolidinol-->Dimethylamine hydrochloride-->(S)-(+)-Mandelic acid-->Pyridinium dichromate-->TETRAETHYLAMMONIUM ACETATE TETRAHYDRATE, 99

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