(3,4-Dimethoxyphenyl)acetic acid

(3,4-Dimethoxyphenyl)acetic acid
  • CAS No.:93-40-3
Other grades of this product :
(3,4-Dimethoxyphenyl)acetic acid Basic information
Product Name:(3,4-Dimethoxyphenyl)acetic acid
Synonyms:3,4-Dimethoxyphenylacetic acid,3,4-Dimethoxyphenylacetic acid, Homoveratric acid;4-DiMethoxyphenylacetic acid;2-(3,4-DiMethoxyphenyl)acetate;(3,4-DiMethoxyphenyl)acetic acid, 99% 100GR;(3,4-DiMethoxyphenyl)acetic acid, 99% 25GR;(3,4-DiMethoxyphenyl)acetic acid, 99% 500GR;NSC 2753;NSC 27897
CAS:93-40-3
MF:C10H12O4
MW:196.2
EINECS:202-244-5
Product Categories:Catechol Derivatives;Aromatic Phenylacetic Acids and Derivatives;Aromatics, Metabolites & Impurities, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals;Inhibitors
Mol File:93-40-3.mol
(3,4-Dimethoxyphenyl)acetic acid Chemical Properties
Melting point 96-98 °C (lit.)
Boiling point 293.08°C (rough estimate)
density 1.2166 (rough estimate)
refractive index 1.5430 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pkapK1:4.333 (25°C)
form Powder
color White to beige
Water Solubility SOLUBLE
BRN 1110282
InChIKeyWUAXWQRULBZETB-UHFFFAOYSA-N
LogP1.242
CAS DataBase Reference93-40-3(CAS DataBase Reference)
NIST Chemistry ReferenceAcetic acid, 3,4-dimethoxyphenyl-(93-40-3)
EPA Substance Registry SystemBenzeneacetic acid, 3,4-dimethoxy- (93-40-3)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-22-36/37
Safety Statements 22-24/25-36/37-26-37/39
WGK Germany 3
RTECS AH0675000
TSCA Yes
HazardClass IRRITANT
HS Code 29189090
MSDS Information
ProviderLanguage
Homoveratric acid English
SigmaAldrich English
ACROS English
ALFA English
(3,4-Dimethoxyphenyl)acetic acid Usage And Synthesis
Chemical Propertieswhite to beige powder
UsesHomoveratric Acid is a dopamine metabolite that inhibits brain mitochondrial respiration via monoamine oxidase/H2O2-dependent or non-dependent pathway.
UsesIt reacts with formaldehyde in the presence of acid to give an isochromanone.
Synthesis Reference(s)Organic Syntheses, Coll. Vol. 2, p. 333, 1943The Journal of Organic Chemistry, 15, p. 548, 1950 DOI: 10.1021/jo01149a016
Purification MethodsCrystallise homoveratric acid from H2O or *C6H6/ligroin. The amide has m 142o (from H2O). [Beilstein 10 H 409, 10 I 197, 10 II 268, 10 III 1459, 10 IV 1509.]

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