Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate

Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate
  • CAS No.:144689-93-0
Other grades of this product :

Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate Basic information
Product Name:Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate
Synonyms:4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;1H-Imidazole-4-carboxylicacid,5-(1-hydroxy-1-met;1H-Imidazole-5-carboxylicacid,4-(1-hydroxy-1-met;ETHYL-4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-IMIDAZOLE-5-CARBOXYLATE;1H-Imidazole-4-carboxylic acid,5-(1-hydroxy-1-methylethyl)-2- propyl-,ethyl ester;Olmesartan intermediate;5-(1-HYDROXYL-1-METHYLETHYL)-2-PROPYL-IMIDAZOL-4-YLCARBOXYLIC ACID ETHYL ESTER;4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 98+%
CAS:144689-93-0
MF:C12H20N2O3
MW:240.3
EINECS:1592732-453-0
Product Categories:API intermediates;Heterocycles;INTERMEDIATESOF;Imidazol&Benzimidazole;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:144689-93-0.mol
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate Chemical Properties
Melting point 98-100°C
Boiling point 456.2±35.0 °C(Predicted)
density 1.131±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform, Ethyl Acetate, Methanol
form Solid
pka11.61±0.10(Predicted)
color Pale Yellow
CAS DataBase Reference144689-93-0(CAS DataBase Reference)
Safety Information
MSDS Information
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesAn Olmesartan (O550000) intermediate.
UsesOlmesartan (O550000) intermediate.
ApplicationEthyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate is a synthetic drug with pharmacological properties that are similar to those of the natural product medoxomil. It has been shown to be a potent blocker of the GABA receptor and is used for the treatment of epilepsy.It has been shown to be an inhibitor of rat liver microsomes and also has a high affinity for the enzyme cilexetil, which is responsible for the conversion of cilexetil into its active form.
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate Preparation Products And Raw materials
Preparation ProductsOlmesartan Medoxomil-->Trityl olmesartan-->Trityl Olmesartan Medoxomil-->1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester

Welcome!

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

  • NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
  • +86-23-6139-8061 +86-13650506873
  • danny@chemdad.com sales@chemdad.com
  • www.chemdad.com
  • WhatsApp +86-13650506873

Name

phone

company

email

message

Payment methods
Google translate: 日本语日本语 한국어한국어 FrançaisFrançais DeutschDeutsch EspañaEspaña TürkiyeTürkiye