2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL

CAS No.：224311-49-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL Basic information

Reaction

Product Name:	2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL
Synonyms:	2'-[Bis(1,1-dimethylethyl)phosphino]-N,N-dimethyl-[1,1'-biphenyl]-2-amine;2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)biphenyl,98%;2-[2-(di-tert-butylphosphanyl)phenyl]-N,N-diMethylaniline;98% tBuDavePhos;2'-(Di-tert-butylphosphino)-N,N-diMethyl-[1,1'-biphenyl]-2-aMine;2-(Di-tert-butylphosphiNA)-2'-(N,N-diMethylaMiNA)biphenyl;2-(Di-tert-butylphosphino)-2'-;2-Di-t-butylphosphino-2'-(N,N-diMethylaMino)biphenyl,98% tBuDavePhos
CAS:	224311-49-3
MF:	C22H32NP
MW:	341.47
EINECS:	607-073-3
Product Categories:	Phosphines;Achiral Phosphine;Aryl Phosphine;Buchwald Ligands Series;Buchwald Ligands&Precatalysts
Mol File:	224311-49-3.mol

2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL Chemical Properties

Melting point	115-117 °C
Boiling point	451.6±38.0 °C(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	5.07±0.18(Predicted)
form	crystal
color	white
Sensitive	Air Sensitive
InChIKey	PHLPNEHPCYZBNZ-UHFFFAOYSA-N

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	37/39-26
WGK Germany	3
TSCA	No
HS Code	29319090

MSDS Information

Provider	Language
ACROS	English

2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL Usage And Synthesis

Reaction	Useful ligand for Pd-catalyzed carbon-oxygen bond forming reactions. Ligand used selective Pd-catalyzed arylation of ammonia. Application to the synthesis of dibenzodiazepines. Ligand used for selective Pd-catalyzed silylation of aryl chlorides. Ligand used for Pd(0)-catalyzed direct dehydrative coupling of terminal alkynes with allylic alcohols to access 1,4-enynes.
Chemical Properties	White crystals or crystalline powder
Uses	suzuki reaction

2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL Preparation Products And Raw materials

Preparation Products

Methanesulfonato2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)

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