3,3-Diethoxypropionitrile
3,3-Diethoxypropionitrile
  • CAS No.:2032-34-0
Other grades of this product :
3,3-Diethoxypropionitrile Basic information
Product Name:3,3-Diethoxypropionitrile
Synonyms:CYANOACETALDEHYDE DIETHYL ACETAL;CYADEA;1,1-DIETHOXY-2-CYANOETHANE;3,3-DIETHOXYPROPIONITRILE;2-CYANOACETALDEHYDE DIETHYLACETAL;3,3-diethoxypropiononitrile;Propanenitrile, 3,3-diethoxy-;3,3-Diethoxypropiononitril
CAS:2032-34-0
MF:C7H13NO2
MW:143.18
EINECS:217-988-6
Product Categories:C6 to C7;Cyanides/Nitriles;Nitrogen Compounds
Mol File:2032-34-0.mol
3,3-Diethoxypropionitrile Chemical Properties
Melting point 82-84
Boiling point 91-93 °C/11 mmHg (lit.)
density 0.954 g/mL at 25 °C (lit.)
refractive index n20/D 1.415(lit.)
Fp 183 °F
storage temp. Inert atmosphere,2-8°C
solubility 32g/l
form Oil
color Clear Colourless to Pale Yellow
InChIKeyWBOXEOCWOCJQNK-UHFFFAOYSA-N
CAS DataBase Reference2032-34-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 3275
WGK Germany 2
Hazard Note Irritant
HS Code 29269095
MSDS Information
ProviderLanguage
1,1-Diethoxy-2-cyanoethane English
ACROS English
SigmaAldrich English
ALFA English
3,3-Diethoxypropionitrile Usage And Synthesis
Chemical PropertiesCLEAR YELLOW TO BROWNISH LIQUID
Uses3,3-Diethoxypropionitrile is a propionitrile derivative used in the preparation of various biologically active compounds such as p38α mitogen-activated protein kinase inhibitors.
Uses3,3-Diethoxypropionitrile may be used in the synthesis of 2-(2,2-diethoxy-ethyl)-pyridine, via [2+2+2]-cycloaddition reaction. It may be used in the synthesis of cyanomalondialdehyde.
Synthesis Reference(s)Journal of the American Chemical Society, 69, p. 2657, 1947 DOI: 10.1021/ja01203a028
General Description3,3-Diethoxypropionitrile is a cyanide derivative. It undergoes reaction with urea in refluxing butanolic sodium butoxide to afford 4-amino-2(1H)-pyrimidinone and cytosine. Its physical properties (density, refractive index, boiling point and melting point) have been reported.

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