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| 5-Fluoroisatin Basic information |
| 5-Fluoroisatin Chemical Properties |
| Melting point | 224-227 °C (lit.) | | density | 1.477±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform, DMSO, Methanol | | pka | 8.51±0.20(Predicted) | | form | Powder | | color | Red | | BRN | 131241 | | InChIKey | GKODDAXOSGGARJ-UHFFFAOYSA-N | | CAS DataBase Reference | 443-69-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29337900 |
| 5-Fluoroisatin Usage And Synthesis |
| Chemical Properties | red Crystalline Powder | | Uses | It showed antibacterial and antifungal activities.
| | Uses | Reactant for preparation of:- Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds
- Potential antimycobacterial agents
- Inhibitors of c-Met kinase
- Inhibitors of TAK1 kinase
- Herpes simplex virus inhibitors
- IKKβ inhibitors
- Inhibitors of vitiligo disease
- Potential drug candidates with anti-HIV activity and anti-tubercular activity
| | General Description | 5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST). |
| 5-Fluoroisatin Preparation Products And Raw materials |
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