| 3-Fluoro-4-methoxyaniline Basic information |
| Product Name: | 3-Fluoro-4-methoxyaniline |
| Synonyms: | 4-AMINO-2-FLUOROANISOLE;3-Fluoro-p-anisidine (NH2=1);3-FLUORO-P-ANISIDINE;3-FLUORO-4-ANISIDINE;3-FLUORO-4-METHOXYANILINE;3-Fluoro-4-Methoxyaniline 2-Fluoro-4-Aminoanisole;4-Amino-2-fluoroanisol;3-Fluoro-4-methoxy-phenylamine |
| CAS: | 366-99-4 |
| MF: | C7H8FNO |
| MW: | 141.14 |
| EINECS: | 627-615-2 |
| Product Categories: | Anilines, Amides & Amines;Anisoles, Alkyloxy Compounds & Phenylacetates;Anilines, Aromatic Amines and Nitro Compounds;Aniline;Miscellaneous;Fluorine Compounds;Other fluorin-contained compounds;bc0001 |
| Mol File: | 366-99-4.mol |
| 3-Fluoro-4-methoxyaniline Chemical Properties |
| Melting point | 81-83 °C (lit.) |
| Boiling point | 135 °C/18 mmHg (lit.) |
| density | 1.1382 (estimate) |
| Fp | >110°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.18±0.10(Predicted) |
| form | Crystalline Powder |
| color | Light beige to yellow-brown |
| BRN | 2717083 |
| CAS DataBase Reference | 366-99-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn,Xi,T |
| Risk Statements | 20/21/22-36/37/38-23/24/25 |
| Safety Statements | 26-37/39-45-38-36/37/39-28A |
| RIDADR | UN2811 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29214200 |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| 3-Fluoro-4-methoxyaniline Usage And Synthesis |
| Chemical Properties | light beige to yellow-brown crystalline powder |
| Uses | 3-Fluoro-4-methoxyaniline was used as a reagent in the synthesis of novel leucine ureido derivatives which have potent inhibitory activity againt aminopeptidase N. Also used in the synthesis of novel mGluR1 antagonists for the treatment of chronic pain. |
| General Description | Arrhenius parameter has been measured for the reactions of 3-fluoro-p-anisidine (3-fluoro-4-methoxyaniline) with picryl chloride. |
| 3-Fluoro-4-methoxyaniline Preparation Products And Raw materials |
| Preparation Products | 4-CHLORO-2-FLUOROANISOLE |
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