Other grades of this product :
| ABT-888 Basic information |
| Product Name: | ABT-888 | | Synonyms: | ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-
carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl;Veliparib hydrochloride | | CAS: | 912445-05-7 | | MF: | C13H16N4O | | MW: | 244.296 | | EINECS: | 1592732-453-0 | | Product Categories: | Inhibitors;Inhibitor;API | | Mol File: | 912445-05-7.mol |
| ABT-888 Chemical Properties |
| Melting point | >173°C (dec.) | | storage temp. | Refrigerator | | solubility | Methanol (Slightly, Heated), THF (Slightly, Heated) | | form | Colorless to white crystalline solid. | | color | Off-White to Dark Yellow |
| ABT-888 Usage And Synthesis |
| Uses | ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Potent PARP inhibitor. |
| ABT-888 Preparation Products And Raw materials |
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