(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
  • CAS No.:156928-09-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Basic information
Product Name:(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
Synonyms:(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol;(3R, 3aS, 6aS)-hexahydrofuro[2,3-b]furan-3-ol;(3R)-hexahydrofuro[2,3-b]furan-3-ol;3-hydroxy-(3R,3αS,6αR)-bis-tetrahydrofuran;Furo[2,3-b]furan-3-ol, hexahydro-, (3R,3aS,6aR;HEXAHYDRO-(3R,3AS,6AR)-FURO(2,3-B)FURAN-3-OL;(3R,3aS,6aR);3-hydroxy-(3R,3±S,6±R)-bis-tetrahydrofuran
CAS:156928-09-5
MF:C6H10O3
MW:130.14
EINECS:605-076-4
Product Categories:
Mol File:156928-09-5.mol
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Chemical Properties
Boiling point 251.5±20.0 °C(Predicted)
density 1.275
vapor pressure 0.19Pa at 25℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka14.07±0.20(Predicted)
form Oil
color Pale Yellow
LogP1.055 at pH5
Safety Information
MSDS Information
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Usage And Synthesis
Uses(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol is used as a reagent in the synthesis of Darunavir (D193500); a second generation HIV-1-protease inhibitor and antiviral agent.
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Preparation Products And Raw materials
Raw materials2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-ol-->2-Furanol, 3-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydro-, (3S)--->809286-93-9-->(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol-->Vinyl acetate
Preparation Products(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol

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