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| (+)-Cloprostenol isopropyl ester Basic information |
| Product Name: | (+)-Cloprostenol isopropyl ester | | Synonyms: | 5-Heptenoic acid,7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-;D-cloprostenol isopropyl ester;ISOPROPYL CLOPROSTENAT;Isopropyl Cloprostenate;(+)-Cloprostenol isopropyl ester;CPG 6112-95;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-;(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester | | CAS: | 157283-66-4 | | MF: | C25H35ClO6 | | MW: | 466.99 | | EINECS: | | Product Categories: | | Mol File: | 157283-66-4.mol |
| (+)-Cloprostenol isopropyl ester Chemical Properties |
| Boiling point | 600.0±55.0 °C(Predicted) | | density | 1.227±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Oil | | pka | 13.41±0.20(Predicted) | | color | Colourless Thick |
| (+)-Cloprostenol isopropyl ester Usage And Synthesis |
| Description | (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with PGF2α. (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 x 10-12 M. (+)-Cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol. | | Uses | Isopropyl Cloprostenate is an isopropyl ester derivative of Cloprostenol (C587300); an aryl-oxymethyl analog of prostaglandin F2α. |
| (+)-Cloprostenol isopropyl ester Preparation Products And Raw materials |
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