Triisopropyl orthoformate

CAS No.：4447-60-3

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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Triisopropyl orthoformate Basic information

Product Name:	Triisopropyl orthoformate
Synonyms:	TRIISOPROPOXYMETHANE;TRIISOPROPYL ORTHOFORMATE;TIPOF;ORTHOFORMIC ACID TRIISOPROPYL ESTER;Triisopropyl orthoformate, anhydrous, AcroSeal, 99.5%;Propane, 2,2,2-methylidynetris(oxy)tris-;2,2′,2′′-[methylidyntris(oxy)]trispropan;2-diisopropoxymethoxy-propane
CAS:	4447-60-3
MF:	C10H22O3
MW:	190.28
EINECS:	224-688-9
Product Categories:	Orthoesters;Acetals/Ketals/Ortho Esters;Organic Building Blocks;Oxygen Compounds;bc0001
Mol File:	4447-60-3.mol

Triisopropyl orthoformate Chemical Properties

Boiling point	65-66 °C/18 mmHg (lit.)
density	0.854 g/mL at 25 °C (lit.)
refractive index	n20/D 1.397(lit.)
Fp	108 °F
storage temp.	Flammables area
form	Liquid
color	Clear colorless
Sensitive	Moisture Sensitive
BRN	1700668
InChIKey	FPIVAWNGRDHRSQ-UHFFFAOYSA-N
CAS DataBase Reference	4447-60-3(CAS DataBase Reference)
EPA Substance Registry System	Propane, 2,2',2''-[methylidynetris(oxy)]tris- (4447-60-3)

Safety Information

Hazard Codes	Xi
Risk Statements	10-36/37/38
Safety Statements	26-36-37/39-16
RIDADR	UN 3272 3/PG 3
WGK Germany	1
F	21
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29159000

MSDS Information

Provider	Language
TIPOF	English
ACROS	English
SigmaAldrich	English
ALFA	English

Triisopropyl orthoformate Usage And Synthesis

Chemical Properties	clear colourless liquid
Uses	Triisopropyl Orthoformate (cas# 4447-60-3) is a compound useful in organic synthesis.
Uses	Triisopropyl orthoformate may be used for the preparation of 2-(diisopropoxymethyl)oxirane.
General Description	Triisopropyl orthoformate (TIPO) is formed during the reaction of dichlorofluoromethane with potassium isopropoxide in isopropyl alcohol. Separation of TIPO from n-hexane by dense carbon nanotube (CNT) membranes by pervaporation has been reported.

Triisopropyl orthoformate Preparation Products And Raw materials

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