| (S)-3-Hydroxypyrrolidine hydrochloride Basic information |
| Product Name: | (S)-3-Hydroxypyrrolidine hydrochloride |
| Synonyms: | (S)-PYRROLIDIN-3-OL HCL;(S)-PYRROLIDINE-3-OL HYDROCHLORIDE;TIMTEC-BB SBB004272;(S)-3-HYDROXY PYRROLIDINE HCL;(S)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE;(S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE;(S)-3-PYRROLIDINOL HYDROCHLORIDE;3-PYRROLIDINOL, HYDROCHLORIDE, (3S) |
| CAS: | 122536-94-1 |
| MF: | C4H10ClNO |
| MW: | 123.58 |
| EINECS: | 672-315-7 |
| Product Categories: | Chiral chemicals;Benzenes;pharmacetical;Pyrrole&Pyrrolidine&Pyrroline;chiral;Heterocyclic Compounds;Alcohols and Derivatives;Intermediate |
| Mol File: | 122536-94-1.mol |
| (S)-3-Hydroxypyrrolidine hydrochloride Chemical Properties |
| Melting point | 104-107°C |
| Boiling point | 108-110℃/8mm |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Beige |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 122536-94-1(CAS DataBase Reference) |
| MSDS Information |
| (S)-3-Hydroxypyrrolidine hydrochloride Usage And Synthesis |
| Chemical Properties | almost white crystalline powder |
| Uses | (S)-3-Hydroxypyrrolidine Hydrochloride is a useful intermediate for the synthesis of Asimadoline Hydrochlorine (A788250), used in the treatment of IBS, a disorder associated with pain and altered bowel function. |
| (S)-3-Hydroxypyrrolidine hydrochloride Preparation Products And Raw materials |
| Raw materials | Ethanol-->Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Acetic acid-->PETROLEUM ETHER-->Lithium Aluminum Hydride-->Sodium borohydride-->Acetyl chloride-->Calcium chloride-->Benzylamine-->HEAVY DISTILLATE-->L-Malic acid |
| Preparation Products | LOXO-101 (sulfate) |
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