Atorvastatin lactone

Atorvastatin lactone
  • CAS No.:125995-03-1

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
Atorvastatin lactone Basic information
Product Name:Atorvastatin lactone
Synonyms:1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide;Atorvastatin EPIMp H (USP RCH);Atorvastatin EP IMpurity H;Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide);Diepoxide Atorvastatin Lactone Diepoxide;Atorvastatin Calcium Impurity D;Atorvastatin Impurity H;(RS) Atorvastatin Lactone
CAS:125995-03-1
MF:C33H33FN2O4
MW:540.62
EINECS:
Product Categories:Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:125995-03-1.mol
Atorvastatin lactone Chemical Properties
Melting point 103-106°C
alpha D +26.05° (c = 1 in chloroform)
Boiling point 674.8±55.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka13.39±0.40(Predicted)
form Solid
color White to Light Yellow
Merck 14,864
Safety Information
MSDS Information
Atorvastatin lactone Usage And Synthesis
Chemical PropertiesSlightly Yellow Solid
UsesAtorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation
UsesAtorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.
Atorvastatin lactone Preparation Products And Raw materials

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