![2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide](/img/125971-96-2.jpg "2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide")
| 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Basic information |
| Product Name: | 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide |
| Synonyms: | M-4;2[2-(4-FLUOROPHENYL)-2-OXO-1-PHENYLETHYL]-4-METHYL-3-OXO-PENTANOIC ACID PHENYLAMIDE;4-FLUORO-ALPHA-(2-METHYL-1-OXOPROPYL-GAMA-OXO)-N,BETA-DIPHENYLBENZENE BUTANEAMIDE;4-FLUORO-ALPHA-[2-METHYL-1-OXOPROPYL-GAMMA(3)-OXO]-N,BETA-DIPHENYLBENZENE BUTANE AMIDE;4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-n,bata-diphenylbenzene butaneamide;4-FLUORO-ALPHA-(2-METHYL-1-OXOPROPYL)-GAMMA-OXO-N, BETA-DIPHENYLBENZENE BUTANAMIDE;4-fluoro-α-(2-methyl-1-oxo-propyl)-γ-oxo-N-β-diphenyl benzene butanamide;(4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butane amide(M-4) |
| CAS: | 125971-96-2 |
| MF: | C26H24FNO3 |
| MW: | 417.47 |
| EINECS: | 603-107-6 |
| Product Categories: | INTERMEDIATES OF ATORVASTATIN;Chemical intermediate for Atorvastatin Calcium;INTERMEDIATESOFATORVASTATIN;Aromatices;Intermediates & Fine Chemicals;Pharmaceuticals;(intermediate of atorvastatin) |
| Mol File: | 125971-96-2.mol |
| 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Chemical Properties |
| Melting point | 196-1980C |
| Boiling point | 631.4±55.0 °C(Predicted) |
| density | 1.211 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly, Sonicated), Ethyl Acetate (Slight |
| pka | 11.52±0.59(Predicted) |
| form | Solid |
| color | White to Off-White |
| PH | 6.49 at 25℃ and 13.64g/L |
| CAS DataBase Reference | 125971-96-2(CAS DataBase Reference) |
| Safety Information |
| MSDS Information |
| 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Usage And Synthesis |
| Chemical Properties | White to Off-White Solid |
| Uses | An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. |
| Uses | An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia |
| 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Preparation Products And Raw materials |
| Raw materials | Aniline-->Benzaldehyde-->Bromoethane-->Ethylenediamine-->β-Alanine-->4-Fluorobenzaldehyde-->5-(2-Hydroxyethyl)-4-methylthiazole-->Methyl isobutyrylacetate |
| Preparation Products | 10-trans-Atorvastatin Acetonide tert-Butyl Ester |
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