| 4-Aminobenzamidine dihydrochloride Basic information |
| Product Name: | 4-Aminobenzamidine dihydrochloride |
| Synonyms: | 4-AMINOBENZAMIDINE DIHYDROCHLORIDE;4-AMINOBENZAMIDINE HCL SALT;BENZENECARBOXIMIDAMIDE, 4-AMINO-, DIHYDROCHLORIDE;P-AMINOBENZAMIDINE DIHCL;P-AMINOBENZAMIDINE DIHYDROCHLORIDE;4-Aminobenzamidine HCl;4-AMINOBENZAMIDINE DIHYDROCHLORIDE, FOR FLUORESCENCE;4-Aminobenzamidine2HCl |
| CAS: | 2498-50-2 |
| MF: | C7H11Cl2N3 |
| MW: | 208.09 |
| EINECS: | 219-692-2 |
| Product Categories: | inhibitor;Imines/AmidinesFluorescent Probes, Labels, Particles and Stains;Anilines, Aromatic Amines and Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Other Fluorescent Labels;Amines;Miscellaneous;Broad Spectrum Inhibitors of Proteolytic Enzyme Classes;Other Fluorescent LabelsEnzyme Inhibitors;Protease InhibitorsFluorescent Stains;Protein Stains;Protein Stains For SpectroscopyProtease Inhibitors;Serine Protease Inhibitors;Fluorescent Labels;Fluorescent Probes, Labels, Particles and Stains;Protease Inhibitors |
| Mol File: | 2498-50-2.mol |
| 4-Aminobenzamidine dihydrochloride Chemical Properties |
| Melting point | >300 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Water |
| form | Fine Crystalline Powder |
| color | White to yellow |
| Sensitive | Hygroscopic |
| BRN | 3692927 |
| Stability: | Hygroscopic |
| InChIKey | GHEHNICLPWTXJC-UHFFFAOYSA-N |
| CAS DataBase Reference | 2498-50-2(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-37/39-36 |
| WGK Germany | 3 |
| RTECS | CV6126500 |
| F | 3-10-21 |
| HS Code | 29252900 |
| MSDS Information |
| Provider | Language |
|---|---|
| 4-Aminobenzamidine dihydrochloride | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| 4-Aminobenzamidine dihydrochloride Usage And Synthesis |
| Chemical Properties | white to yellowish fine crystalline powder |
| Uses | 4-Aminobenzamidine dihydrochloride is a synthetic diamidine derivative that acts as a urokinase inhibitor as well as trypsin inhibitor. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes. |
| Application | 4-Aminobenzamidine dihydrochloride can be used to synthesize:Orally active fibrinogen receptor antagonists based on benzamidines.Benzamidine derivatives that are selective and potent serine protease inhibitors.Novel pyrrolo [3,2-c] quinolines that are structural analogs of topoisomerase inhibitors such as coralyne and fagaronine.Synthesis of a selective inhibitor of PRMT1 (SKLB-639) |
| Preparation | 4-Aminobenzamididine dihydrochloride is obtained by cyanation, addition, amination and reduction of 4-nitrobenzoic acid. |
| 4-Aminobenzamidine dihydrochloride Preparation Products And Raw materials |
| Raw materials | Ethanol-->Hydrochloric acid-->Methanol-->Sodium-->Acetone-->Palladium-->Ammonium chloride-->Iron-->Sodium methoxide-->Tin-->STANNOUS CHLORIDE-->p-Nitrobenzoic acid-->Tetrabutylammonium fluoride-->Benzhydrylamine-->Ferrous sulfide-->4-Nitrobenzonitrile-->Benzenecarboximidic acid, 4-nitro-, methyl ester |
| Preparation Products | Dabigatran Etexilate iMpurity I |
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