2-Naphthyl acetate

CAS No.：1523-11-1

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-Naphthyl acetate Basic information

Product Name:	2-Naphthyl acetate
Synonyms:	ACETIC ACID 2-NAPHTHYL ESTER;2-NAPHTHYL ACETATE;2-Naphthalenol,acetate;2-Naphthol, acetate;Acetic acid beta-naphthyl ester;beta-Naphthol acetate;Naphthalene, 2-acetoxy-;O-Acetyl-beta-naphthol
CAS:	1523-11-1
MF:	C12H10O2
MW:	186.21
EINECS:	216-194-7
Product Categories:	Aromatic Esters
Mol File:	1523-11-1.mol

2-Naphthyl acetate Chemical Properties

Melting point	67-70 °C (lit.)
Boiling point	132 °C / 2mmHg
density	1.1032 (rough estimate)
refractive index	1.6010 (estimate)
storage temp.	-20°C
solubility	methanol: 0.1 g/mL, clear
form	powder to crystaline
color	White to Light yellow
Sensitive	Moisture Sensitive
BRN	1868291
CAS DataBase Reference	1523-11-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Naphthyl acetate(1523-11-1)
EPA Substance Registry System	2-Naphthalenol, acetate (1523-11-1)

Safety Information

Hazard Codes	Xi
Risk Statements	41
Safety Statements	26-39
WGK Germany	3
F	10-21
TSCA	Yes
HS Code	2916399090

MSDS Information

Provider	Language
2-Naphthyl acetate	English
ACROS	English
SigmaAldrich	English
ALFA	English

2-Naphthyl acetate Usage And Synthesis

Chemical Properties	WHITE FLUFFY POWDER
Uses	2-Naphthyl Acetate is used in the staining of gels for esterase activity in the biological laboratories. An esterase substrate.
Uses	2-Naphthyl acetate has been used as a substrate: in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens in the preparation of zymograms to identify proteins with lipase activity to measure non-specific esterase activity and β-esterase enzyme activity
Synthesis Reference(s)	Journal of the American Chemical Society, 91, p. 2162, 1969 DOI: 10.1021/ja01036a081
Purification Methods	Distil the acetate in a high vaccum and/or crystallise it from pet ether (b 60-80o) or dilute aqueous EtOH. The picrate has m 80o (from EtOH). [Beilstein 6 H 644, 6 I 313, 6 II 600, 5 III 2982, 6 IV 4267.]

2-Naphthyl acetate Preparation Products And Raw materials

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