5-Hydroxyanthranilic acid

CAS No.：394-31-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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5-Hydroxyanthranilic acid Basic information

Product Name:	5-Hydroxyanthranilic acid
Synonyms:	5-HYDROXYANTHRANILIC ACID;5-HYDROXYANTHRANILLIC ACID;2-AMINO-5-HYDROXYBENZOIC ACID;TIMTEC-BB SBB007820;SALOR-INT L308757-1EA;2-Amino-5-Hydroxybenzoic;5-Hydroxyanthranilic;2-Amino-5-HydroxybenzoicAcid98%
CAS:	394-31-0
MF:	C7H7NO3
MW:	153.14
EINECS:	628-812-6
Product Categories:	Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Carboxylic Acids;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het;Amines;FINE Chemical & INTERMEDIATES;Alcohols and Derivatives;Amino Acids and Derivatives;Aromatics;Intermediates
Mol File:	394-31-0.mol

5-Hydroxyanthranilic acid Chemical Properties

Melting point	247 °C (dec.) (lit.)
Boiling point	276.03°C (rough estimate)
density	1.3585 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Crystalline Powder
pka	2.08±0.10(Predicted)
color	Gray-brownish
Water Solubility	Insoluble
BRN	2803663
CAS DataBase Reference	394-31-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38-20/22
Safety Statements	26-36-36/37/39
WGK Germany	3
HS Code	29225090

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

5-Hydroxyanthranilic acid Usage And Synthesis

Chemical Properties	white crystalline powder
Uses	An oral anti-diabetic drug.
Application	5-Hydroxyanthranilic acid can be used as an intermediate of azo and sulfur dyes for the manufacture of photosensitive paper.
Purification Methods	Crystallise the acid from water. The benzamide has m 240-242o (fromAcOH). It is a hypoglycemic agent.[Beilstein 14 H 591, 14 II 357, 14 III 1468, 14 IV 2080.]

5-Hydroxyanthranilic acid Preparation Products And Raw materials

Raw materials	Ethanol-->Potassium hydroxide-->Dimethyl sulfoxide-->Sodium dithionite-->Copper-->5-Chloro-2-nitrobenzoic acid
Preparation Products	Fomesafen-->6-HYDROXY-3,4-DIHYDROQUINAZOLONE-->5-Hydroxy-2-nitrobenzoic acid-->6-METHOXY-QUINAZOLIN-4-YLAMINE

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