3-Phenylpropionic acid methyl ester

CAS No.：103-25-3

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3-Phenylpropionic acid methyl ester Basic information

Product Name:	3-Phenylpropionic acid methyl ester
Synonyms:	Benzenepropanoic acid, methyl ester;benzenepropanoicacid,methylester;beta-Phenylpropionic acid methyl ester;Hydrocinnamic acid, methyl ester;methyl (3-phenyI) propanoate;Methyl 3-phenylpropanoate;Methyl benzenepropanoate;Methyl beta-phenylpropionate
CAS:	103-25-3
MF:	C10H12O2
MW:	164.2
EINECS:	203-092-2
Product Categories:	Pharmaceutical Intermediates;Aromatic Cinnamic Acids, Esters and Derivatives;Organic acids;103-25-3
Mol File:	103-25-3.mol

3-Phenylpropionic acid methyl ester Chemical Properties

Melting point	142-145 °C
Boiling point	91-92 °C4 mm Hg(lit.)
density	1.043 g/mL at 25 °C(lit.)
refractive index	n20/D 1.502(lit.)
FEMA	2741 \| METHYL 3-PHENYLPROPIONATE
Fp	212 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
color	Colourless to Pale Yellow
Water Solubility	Soluble in chloroform. Insoluble in water.
JECFA Number	643
BRN	1909591
InChIKey	RPUSRLKKXPQSGP-UHFFFAOYSA-N
CAS DataBase Reference	103-25-3(CAS DataBase Reference)
NIST Chemistry Reference	3-Phenylpropanoic acid methyl ester(103-25-3)
EPA Substance Registry System	Benzenepropanoic acid, methyl ester (103-25-3)

Safety Information

Safety Statements	24/25
WGK Germany	2
TSCA	Yes
HS Code	29163990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

3-Phenylpropionic acid methyl ester Usage And Synthesis

Description	Methyl 3-phenylpropionate has a strong floral-fruity odor. May be prepared by reduction of methyl cinnamate in methanol solution with hydrogen and Ni under pressure.
Chemical Properties	Methyl-3-phenylpropionate has a strong floral–fruity odor, with honey and wine-like undertones
Chemical Properties	Clear light yellow liquid
Occurrence	Reported found in tabasco peppers, grapes, rhubarb, soursop and basil
Uses	3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients.
Uses	Methyl 3-phenylpropionate, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. 3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients. It is also used as an application, aromatic intermediate.
Preparation	By reduction of methyl cinnamate in methanol solution with hydrogen and Ni under pressure
Aroma threshold values	Aroma characteristics at 1.0%: sweet, rich spicy Ceylon cinnamonlike, balsamic with fruity, resinous and powdery nuances
Taste threshold values	Taste characteristics at 5 ppm: cinnamon spicy, sweet, balsamic with fruity floral and resinous nuances.
Synthesis Reference(s)	Tetrahedron Letters, 30, p. 5293, 1989 DOI: 10.1016/S0040-4039(01)93768-2Journal of the American Chemical Society, 95, p. 625, 1973 DOI: 10.1021/ja00783a073

3-Phenylpropionic acid methyl ester Preparation Products And Raw materials

Raw materials	Benzene, (2,2-dimethoxycyclopropyl)--->A-(HYDROXYMETHYL)BENZENACETIC ACID METHYL ESTER-->Methyl cinnamate
Preparation Products	Methyl -chloro-hydroxy benzenepropanoate-->(3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-2-one-->3-Phenyl-1-propanol

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