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| MITRAGYNINE PICRATE Basic information |
| Product Name: | MITRAGYNINE PICRATE | | Synonyms: | (αE,2S,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-8-Methoxy-α-(MethoxyMethylene)-indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester;16,17-Didehydro-9,17-diMethoxy-corynan-16-carboxylic Acid Methyl Ester;(16E,20beta)-16,17-Didehydro-9,17-dimethoxy-corynan-16-carboxylic acid methyl ester;MITRAGYNINE(AS);(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-;9-Methoxycorynantheidine;MITRAGYNINE(SH);Mitragynin | | CAS: | 4098-40-2 | | MF: | C23H30N2O4 | | MW: | 398.5 | | EINECS: | 200-659-6 | | Product Categories: | Aromatics;Chiral Reagents;Alkaloids;Intermediates & Fine Chemicals;Pharmaceuticals;Neurochemicals | | Mol File: | 4098-40-2.mol |
| MITRAGYNINE PICRATE Chemical Properties |
| Melting point | 92-95°C | | alpha | D +39° (chloroform) | | Boiling point | bp5 230-240° | | density | 1.22±0.1 g/cm3 (20 ºC 760 Torr) | | Fp | 9℃ | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 18.35±0.60(Predicted) | | color | Light Orange to Dark Beige to Very Dark Yellow |
| MITRAGYNINE PICRATE Usage And Synthesis |
| Description | This alkaloid has been isolated from Mitragyna speciosa Korth, and is amorphous
although it yields a series of crystalline salts and derivatives. The hydrochloride
crystallizes as colourless leaflets from EtOH-Et20 with m.p. 243°C; the picrate
forms thin, orange-red needles, m.p. 223-4°C and the methiodide is a pale
yellow powder which, although amorphous, has a sharp melting point of
21 1. 5°C. The alkaloid also forms compounds with acetic acid, m.p. 142°C,
decomposing at 175-6°, and with trichloroacetic acid, m.p. 157°C.Mitragynine exerts a general depressant effect on plain muscle and facilitates
the passage of autonomic impulses. It is, however, ineffective against pathogenic
organisms. | | Chemical Properties | White to Off-White Solid | | Uses | Mitragynine is a neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynine is being investigated for its ability to treat hard drug addiction. | | Uses | A neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynin is being investigated for its ability to treat hard drug addiction. | | References | Field., J. Chern. Soc., 119,887 (1921)Raymond-Hamet, Millat., Bull. sci. pharrnacol., 40, 593 (1933)lng, Raison., J. Chern. Soc., 986 (1939)Loudon., Chern. Soc. Spec. Publ., 3, 12 (1955)Hendrickson., Chern. & Ind., 713 (1961)Joshi, Raymond-Hamet, Taylor., ibid, 573 (1963)Pharmacology:
Grewal., J. Pharrn. expo Ther., 46,251 (1932) |
| MITRAGYNINE PICRATE Preparation Products And Raw materials |
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