4-Chloro-6-ethyl-5-fluoropyrimidine

CAS No.：137234-74-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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4-Chloro-6-ethyl-5-fluoropyrimidine Basic information

Product Name:	4-Chloro-6-ethyl-5-fluoropyrimidine
Synonyms:	4-chloro-6-ethyl-5-fluoropyiMidine;4-CHLORO-6-ETHYL-5-FLUOROPYRIMIDINE;4-chloro-6-ethyl-5-flouropyrimidine;6-CHLORO-4-ETHYL-5-FLUORO-1,6-DIHYDROPYRIMIDINE;4-Chloro-6-ethyl-5-fluoropyrimidine （Voriconazole）;Voriconazole Impurity 26;4-Chloro-6-ethyl-5-fluoropyrimidin;4-Chloro-5-fluoro-6-ethylpyriMidine
CAS:	137234-74-3
MF:	C6H6ClFN2
MW:	160.58
EINECS:	604-010-1
Product Categories:	Fluorine series;Pharmaceuticals;APIs & Intermediate;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pyrimidine
Mol File:	137234-74-3.mol

4-Chloro-6-ethyl-5-fluoropyrimidine Chemical Properties

Boiling point	211°C
density	1.286
Fp	81°C
refractive index	1.496
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform, Ethyl Acetate
pka	-0.45±0.26(Predicted)
form	Oil
color	Clear Colourless to Pale Yellow
CAS DataBase Reference	137234-74-3(CAS DataBase Reference)

Safety Information

Risk Statements	20/21/22-36/37/38-41
Safety Statements	22-36/37/39-45-39-26
RIDADR	UN3267
HazardClass	8
HS Code	2933599590

MSDS Information

4-Chloro-6-ethyl-5-fluoropyrimidine Usage And Synthesis

Chemical Properties	4-Chloro-6-ethyl-5-fluoropyrimidine is Yellow Liquid
Uses	4-Chloro-6-ethyl-5-fluoropyrimidine is a pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.
Uses	A pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.

4-Chloro-6-ethyl-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials	4-Ethyl-5-fluoro-6-hydroxypyrimidine-->Ethyl 2-fluoro-3-oxopentanoate-->Pentanoic acid, 2-chloro-3-oxo-, ethyl ester-->2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE
Preparation Products	6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine

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