3-AMINO-ISONICOTINIC ACID ETHYL ESTER

CAS No.：14208-83-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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3-AMINO-ISONICOTINIC ACID ETHYL ESTER Basic information

Product Name:	3-AMINO-ISONICOTINIC ACID ETHYL ESTER
Synonyms:	Ethyl3-amino-4-pyridinecarboxylate;3-Amino-isonicotinic acid ethyl ester ,98%;Isonicotinic acid, 3-amino-, ethyl ester (8CI);Ethyl 3-aminopyridine-4-carboxylate, 4-(Ethoxycarbonyl)pyridin-3-amine;ethyl 3-aMinopyridin-4-carboxylate;ETHYL 3-AMINOPYRIDINE-4-CARBOXYLATE;3-AMINOPYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER;3-AMINO-ISONICOTINIC ACID ETHYL ESTER
CAS:	14208-83-4
MF:	C8H10N2O2
MW:	166.18
EINECS:
Product Categories:	Heterocycle-Pyridine series;Pyridine;pharmacetical;Esters;Pyridines;API intermediates;Pyrazoles
Mol File:	14208-83-4.mol

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Chemical Properties

Melting point	170-175
Boiling point	304.0±22.0 °C(Predicted)
density	1.192±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	4.13±0.18(Predicted)
color	Light orange to Yellow to Green
CAS DataBase Reference	14208-83-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39-45
Hazard Note	Irritant
HS Code	29339900

MSDS Information

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Usage And Synthesis

Chemical Properties	Off-white powder or chunks solid
Uses	3-Amino-isonicotinic Acid Ethyl Ester acts as a reagent for the synthetic preparation of heteroaryl compounds as PDE-10 inhibitors useful in treatment and prevention of CNS, metabolic and other diseases. Also in the design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.

3-AMINO-ISONICOTINIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Methanol-->Acetic acid-->Thionyl chloride-->Sodium carbonate-->Chloroform-->Government regulation-->Magnesium sulfate-->Acetic anhydride-->Acetamide-->tert-Butyl methyl ether-->3,4-Pyridinedicarboxylic acid

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