Product

Ethyl N-Boc-piperidine-4-carboxylate

CAS No.：142851-03-4

Other grades of this product :

Ethyl N-Boc-piperidine-4-carboxylate Basic information

Product Name:	Ethyl N-Boc-piperidine-4-carboxylate
Synonyms:	N-BOC-4-CARBETHOXY PIPERIDINE;PIPERIDINE-1,4-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-ETHYL ESTER;1-BOC-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;1-TERT-BUTYL 4-ETHYL 1,4-PIPERIDINEDICARBOXYLATE;1-TERT-BUTYL 4-ETHYL PIPERIDINE-1,4-DICARBOXYLATE;1-(TERT-BUTYL) 4-ETHYL TETRAHYDRO-1,4(2H)-PYRIDINEDICARBOXYLATE;Ethyl N-Boc-piperidine-4-carboxylate;N-BOC-4-piperidine forMic acid ethyl ester
CAS:	142851-03-4
MF:	C13H23NO4
MW:	257.33
EINECS:
Product Categories:	Esters;Pyrans, Piperidines &Piperazines;Amino Acids and Derivatives;Heterocycles;Pyrans, Piperidines & Piperazines
Mol File:	142851-03-4.mol

Ethyl N-Boc-piperidine-4-carboxylate Chemical Properties

Boiling point	120-135 °C/0.5 mmHg
density	1.046 g/mL at 25 °C
refractive index	n20/D 1.458
Fp	>230 °F
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform, Ethyl Acetate
pka	-2.23±0.40(Predicted)
form	Liquid
color	Clear colorless to pale yellow
InChIKey	MYHJCTUTPIKNAT-UHFFFAOYSA-N
CAS DataBase Reference	142851-03-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-37/38-41
Safety Statements	26-39
WGK Germany	3
HazardClass	IRRITANT
HS Code	29333990

MSDS Information

Provider	Language
SigmaAldrich	English

Ethyl N-Boc-piperidine-4-carboxylate Usage And Synthesis

Chemical Properties	Liquid
Uses	Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent to synthesize 3-amino-1-(5-indanyloxy)-2-propanol derivatives as sodium channel blockers to treat stroke patients. Ethyl N-Boc-piperidine-4-carboxylate is also used as a reagent to prepare inhibitors of tumour necrosis factor alpha-converting enzyme.
Uses	Substrate used in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides leading to, for example, 4-pyridylpiperidinyl esters.

Ethyl N-Boc-piperidine-4-carboxylate Preparation Products And Raw materials

Preparation Products

2-Oxa-8-azaspiro[4.5]decane-->1-Boc-4-[methoxy(methyl)carbamoyl]piperidine

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