Indole-2-carboxaldehyde

Indole-2-carboxaldehyde
  • CAS No.:19005-93-7
Other grades of this product :
Indole-2-carboxaldehyde Basic information
Product Name:Indole-2-carboxaldehyde
Synonyms:1H-INDOLE-2-CARBALDEHYDE;1H-INDOLE-2-CARBOXALDEHYDE;2-Formylindole;1H-Indole-2-carboxaldehyde (9CI);Indole-2-carboxaldehyde;1-H-Indole-2-carbaxaldehyde;1H-indole-2-carbaldehyde(SALTDATA: FREE);2-Formyl-1H-indole
CAS:19005-93-7
MF:C9H7NO
MW:145.16
EINECS:
Product Categories:Building Blocks;Heterocyclic Building Blocks;ALDEHYDE;Indoles
Mol File:19005-93-7.mol
Indole-2-carboxaldehyde Chemical Properties
Melting point 138-142 °C
Boiling point 339.1±15.0 °C(Predicted)
density 1.278±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in Methanol.
pka15.05±0.30(Predicted)
form Solution
color Clear pale yellow to grey
Sensitive Air Sensitive
InChIKeySBNOTUDDIXOFSN-UHFFFAOYSA-N
CAS DataBase Reference19005-93-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
Indole-2-carboxaldehyde Usage And Synthesis
UsesIndole-2-carboxaldehyde is a useful starter in indole and natural product chemistry.
Synthesis Reference(s)Tetrahedron, 36, p. 2505, 1980 DOI: 10.1016/0040-4020(80)80230-4
Purification MethodsRecrystallise the indole from aqueous MeOH (m 141-142o), Et2O (m 138o) or sublime it in vacuo (m 138o).The N,N-dimethylhydrazone [127280-17-5] has m 105-106o (from hexane/*C6H6). The thiosemicarbazone has m 229o (dec) (from 50% aqueous EtOH) [Doyle et al. J Chem Soc 2854 1956]. The 2,4-dinitrophenylhydrazone has m 315-320o (dec) (from pyridine/MeOH). [Suzuki et al. Chem Pharm Bull Jpn 39 2170 1991, Beilstein 21 III/IV 3754.]
Indole-2-carboxaldehyde Preparation Products And Raw materials
Raw materialsPyrazino[1,2-a:4,5-a]diindole-6,13-dione
Preparation ProductsN-ACETYLINDOLE-3-CARBOXALDEHYDE-->1H-INDOL-2-YLMETHANOL

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