4-Aminophenylboronic acid pinacol ester

4-Aminophenylboronic acid pinacol ester
  • CAS No.:214360-73-3
Other grades of this product :

4-Aminophenylboronic acid pinacol ester Basic information
Product Name:4-Aminophenylboronic acid pinacol ester
Synonyms:2-(4-AMINOPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;4-Aminophenylboronic acid pinacol ester 97%;4-Aminophenylboronic acid picol ester;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, 2-(4-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;BenzenaMine, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;4-Aminophenylboronic acid pinacol ester    4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneamine;4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENAMINE
CAS:214360-73-3
MF:C12H18BNO2
MW:219.09
EINECS:629-061-7
Product Categories:organic or inorganic borate;B (Classes of Boron Compounds);Substituted Boronic Acids;Boronic Acid;Boronic Acids Esters;CHIRAL  CHEMICALS;Boron compounds
Mol File:214360-73-3.mol
4-Aminophenylboronic acid pinacol ester Chemical Properties
Melting point 165-169 °C (lit.)
Boiling point 340.0±25.0 °C(Predicted)
density 1.05±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform
pka4.24±0.10(Predicted)
form Crystalline Powder
color Almost white to light beige
Water Solubility Insoluble
InChIKeyZANPJXNYBVVNSD-UHFFFAOYSA-N
CAS DataBase Reference214360-73-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
TSCA No
HazardClass IRRITANT
HS Code 29319090
MSDS Information
ProviderLanguage
ACROSEnglish
SigmaAldrichEnglish
4-Aminophenylboronic acid pinacol ester Usage And Synthesis
Chemical Propertiesalmost white to light beige crystalline powder
Usessuzuki reaction
Uses4-Aminophenylboronic acid pinacol ester can be used as a reagent for:
  • The preparation of substituted 3-phenyl-4H-1-benzopyran-4-ones by reacting with iodochromones via Pd catalyzed Suzuki-Miyaura cross-coupling reaction.

  • Mercury(II) detection by fluorometry with new fluorogenic indicators based on through-bond energy transfer from pentaquinone to rhodamine.

  • Rhodium-catalyzed amination reactions.

  • Palladium-catalyzed Suzuki cross-coupling to synthesize potential antitubercular and antimicrobial compounds.

It can also be used to prepare:
  • Hexaphenylbenzene derivatives as a potential bioprobe and multichannel keypad system.

  • Pyromellitic diimide-based polymer as matrix for solution-processable n-channel field-effect transistors.

  • Alternating copolymers of oligoarylenes and naphthalene bisimides as low band-gap semiconductors with electrochemical and spectroelectrochemical behavior.

  • γ-secretase modulators in the treatment of amyloid β formation.

4-Aminophenylboronic acid pinacol ester Preparation Products And Raw materials
Raw materialsTriethylamine-->1,4-Dioxane-->Palladium (II) Acetate-->4-Bromoaniline-->(OXYDI-2,1-PHENYLENE)BIS(DIPHENYLPHOSPHINE)-->Pinacolborane
Preparation Products4-Aminophenylboronic acid-->4-(N-METHYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER-->4'-(4-AMINOPHENYL)-2,2':6',2''-TERPYRIDINE-->4-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER-->4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID-->4,4''-DIAMINO-P-TERPHENYL

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