Cyclopropyl 2-fluorobenzyl ketone

CAS No.：150322-73-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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Cyclopropyl 2-fluorobenzyl ketone Basic information

Description References

Product Name:	Cyclopropyl 2-fluorobenzyl ketone
Synonyms:	Cyclopropyl 2-fluorobenzyl ketone;Ethanone, 1-cyclopropyl-2-(2-fluorophenyl)-;2-fluorobenzyl cyclopropyl ketone;1-CYCLOPROPYL-2-(2-FLUORO-PHENYL)-ETHANONE;1-cyclopropyl-2-(2-fluorophenyl)-Ethanone (prasugrel);Chemical intermediate for Prasugrel, Cyclopropyl 2-fluorobenzyl ketone;prasugrl I;150322-73-91
CAS:	150322-73-9
MF:	C11H11FO
MW:	178.2
EINECS:	1592732-453-0
Product Categories:	Aromatics;Intermediates;Drug Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals;Erlotinib;1
Mol File:	150322-73-9.mol

Cyclopropyl 2-fluorobenzyl ketone Chemical Properties

Boiling point	61°C/0.2mmHg(lit.)
density	1.192±0.06 g/cm3(Predicted)
refractive index	1.5150-1.5190
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig
form	Oil
color	Colourless to Light Yellow
InChIKey	DWBGTJUQWKWYGB-UHFFFAOYSA-N
CAS DataBase Reference	150322-73-9(CAS DataBase Reference)

Safety Information

HS Code

2933399990

MSDS Information

Cyclopropyl 2-fluorobenzyl ketone Usage And Synthesis

Description	Cyclopropyl 2-fluorobenzyl ketone is a kind of ketone derivative. It is a kind of pharmacological intermediate. It is a pharmacological intermediate during the preparation of Prasugrel which is a kind of platelet inhibitors used for preventing the formation of blood clots.
References	Al Omari, Mahmoud MH, et al. "Chapter Four-Prasugrel Hydrochloride."Profiles of Drug Substances, Excipients and Related Methodology 40 (2015): 195-320.
Chemical Properties	Pale Yellow Oil
Uses	Atomoxetine intermediate
Uses	Prasugrel intermediate.
Uses	Prasugrel intermediate

Cyclopropyl 2-fluorobenzyl ketone Preparation Products And Raw materials

Raw materials

2-Fluorophenylacetic acid-->2-(2-FLUOROPHENYL)-N-METHOXY-N-METHYLACETAMIDE-->N,N-DIMETHYLCYCLOPROPANECARBOXAMIDE-->METHYL 2-FLUOROPHENYLACETATE-->N,N-diethylcyclopropanecarboxaMide-->1,2-Bis(2-fluorophenyl)ethane-->Ethyl cyclopropanecarboxylate-->Methyl cyclopropane carboxylate-->alpha-Chloro-o-fluorotoluene-->ETHYL 2-FLUOROPHENYLACETATE-->2-Fluorobenzyl alcohol

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