| 2-Chlorobenzimidazole Basic information |
| Product Name: | 2-Chlorobenzimidazole |
| Synonyms: | 1H-Benzimidazole, 2-chloro-;2-chloro-1h-benzimidazol;Benzimidazole, 2-chloro-;TIMTEC-BB SBB006585;2-CHLORO-1H-BENZIMIDAZOLE;2-CHLORO-1H-BENZOIMIDAZOLE;2-CHLOROBENZIMIDAZOLE;AKOS B028974 |
| CAS: | 4857-06-1 |
| MF: | C7H5ClN2 |
| MW: | 152.58 |
| EINECS: | 225-453-3 |
| Product Categories: | Benzimidazoles;BenzimidazolesHeterocyclic Building Blocks;BENZIMIDAZOLE;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PHARMACEUTICAL INTERMEDIATES;Imidazol&Benzimidazole;(intermediates of norastemizole hcl) |
| Mol File: | 4857-06-1.mol |
| 2-Chlorobenzimidazole Chemical Properties |
| Melting point | 207-211 °C (lit.) |
| Boiling point | 250.67°C (rough estimate) |
| density | 1.2763 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 9.81±0.10(Predicted) |
| form | Crystalline Powder |
| color | Beige to brown |
| Water Solubility | Insoluble in water. |
| Sensitive | Moisture Sensitive |
| BRN | 116526 |
| CAS DataBase Reference | 4857-06-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Chlorobenzimidazole(4857-06-1) |
| EPA Substance Registry System | 1H-Benzimidazole, 2-chloro- (4857-06-1) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29332900 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2-Chlorobenzimidazole Usage And Synthesis |
| Chemical Properties | BEIGE TO BROWN CRYSTALLINE POWDER |
| Uses | 2-Chlorobenzimidazole is mainly used for the synthesis of medicine and as an intermediate in organic synthesis. |
| Application | 2-Chlorobenzimidazole can be used to synthesize the following: 1-methyl-2-chlorobenzimidazole via reaction with dimethyl sulfate1-ethyl-2-chlorobenzimidazole via reaction with diethyl sulfate1-benzyl-2-chlorobenzimidazole via reaction with benzyl chloride2-chloro-4,5,6,7-tetrabromobenzimidazole via bromination with bromineIt may be used as a building block to synthesize 4-amino-6-benzimidazole-pyrimidines. |
| General Description | 2-Chlorobenzimidazole can be synthesized by reacting benzimidazole-2-one with phosphoryl chloride in the presence of phenol. |
| 2-Chlorobenzimidazole Preparation Products And Raw materials |
| Preparation Products | Emedastine-->Lerisetron |
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.
日本语
한국어
Français
Deutsch
España
Türkiye