(-)-Arctigenin

(-)-Arctigenin
  • CAS No.:7770-78-7
Other grades of this product :
(-)-Arctigenin Basic information
Product Name:(-)-Arctigenin
Synonyms:(3R,4R)-4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-2(3H)-FURANONE;2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL];ARCTIGENIN:2(3H)-FURANONE,4-[(3,4-DIMETHOXYPHENYL)METHYL]DIHYDRO-3-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-,(3R,4R);2(3H)-Furanone,4-[(3,4-dimethoxyphenyl) methyl];dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-,(3R,4R)-;(-)-ARCTIGENIN;ARCTIGENIN
CAS:7770-78-7
MF:C21H24O6
MW:372.41
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Miscellaneous Natural Products;Protein Kinase
Mol File:7770-78-7.mol
(-)-Arctigenin Chemical Properties
Melting point 98.0 to 102.0 °C
Boiling point 567.0±45.0 °C(Predicted)
density 1.227±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: 34 mg/mL with heating and sonicating, soluble
form solid
pka10.03±0.20(Predicted)
color White to Light yellow
λmax280nm(EtOH)(lit.)
InChIKeyNQWVSMVXKMHKTF-JKSUJKDBSA-N
CAS DataBase Reference7770-78-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS LY9247000
MSDS Information
ProviderLanguage
SigmaAldrich English
(-)-Arctigenin Usage And Synthesis
UsesArctigenin is a plant ligan associated with anticancer and antioxidant properties.
Biological ActivityAntioxidant, anti-inflammatory, antiproliferative and antiviral agent. Inhibits LPS-induced iNOS expression via inhibition of I κ B α phosphorylation and p65 nuclear translocation (IC 50 = 10 nM). Inhibits HIV-1 replication in vitro . Also potently inhibits MKK1 (IC 50 = 0.5 nM) and provides neuroprotection by binding to kainate receptors.
(-)-Arctigenin Preparation Products And Raw materials

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