pyridine-3-sulfonyl chloride

CAS No.：16133-25-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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pyridine-3-sulfonyl chloride Basic information

Product Name:	pyridine-3-sulfonyl chloride
Synonyms:	3-CHLOROSULFONYL-PYRIDINIUM, CHLORIDE;3-PYRIDINESULFONYL CHLORIDE, HCL;3-PYRIDINESULFONYL CHLORIDE HYDROCHLORIDE;PYRIDINE-3-SULPHONYL CHLORIDE HYDROCHLORIDE;3-Pyridine sulphonyl chloride;m-Pyridinesulfonyl chloride;Piperidine-3-sulfonylchloride;Vonoprazan intermediate
CAS:	16133-25-8
MF:	C5H4ClNO2S
MW:	177.61
EINECS:	688-270-1
Product Categories:
Mol File:	16133-25-8.mol

pyridine-3-sulfonyl chloride Chemical Properties

Melting point	144 °C
Boiling point	284℃
density	1.488
Fp	126℃
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	-1.77±0.11(Predicted)
InChIKey	CDRNYKLYADJTMN-UHFFFAOYSA-N
LogP	1.75
CAS DataBase Reference	16133-25-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,C
Risk Statements	34-43
Safety Statements	26-36/37/39-45
RIDADR	3261
WGK Germany	3
HazardClass	IRRITANT
PackingGroup	Ⅲ
HS Code	2933399990

MSDS Information

pyridine-3-sulfonyl chloride Usage And Synthesis

Uses	3-pyridinesulfonyl Chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.

pyridine-3-sulfonyl chloride Preparation Products And Raw materials

Raw materials	Dichloromethane-->N,N-Dimethylformamide-->Thionyl chloride-->3-Pyridinesulfonic acid
Preparation Products	2-Pyridinesulfonamide(6CI,7CI,9CI)

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