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| 6-Aminoindazole Basic information |
| 6-Aminoindazole Chemical Properties |
| Melting point | 204-206 °C (dec.) (lit.) | | Boiling point | 376.6±15.0 °C(Predicted) | | density | 1.367±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | pka | 15.61±0.40(Predicted) | | form | Powder | | color | Tan | | InChIKey | KEJFADGISRFLFO-UHFFFAOYSA-N | | CAS DataBase Reference | 6967-12-0(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | RTECS | NK7712000 | | HS Code | 29339980 |
| 6-Aminoindazole Usage And Synthesis |
| Description | 6-Aminoindazole is a tetronic acid derivative that has been shown to have an inhibitory effect on the activity of cyclopentyl and ethylene diamine. This drug also increases blood pressure in animals, and is found to be a potent inhibitor of thrombin receptor. | | Chemical Properties | light brown powder | | Application | 6-Aminoindazole is structurally similar to quinoline derivatives and has been shown to have anticancer activity in human ovarian carcinoma cells. The affinity constants for this compound are higher than those for most other compounds with anti-cancer effects, which may be due to the presence of hydrogen bonds between the nitrogen atoms and the carbonyl group. | | Purification Methods | It is recrystallised from H2O or EtOH and sublimes in a vacuum. [Beilstein 25 H 317.] |
| 6-Aminoindazole Preparation Products And Raw materials |
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