| 2-Amino-4-chloropyrimidine Basic information |
| Product Name: | 2-Amino-4-chloropyrimidine |
| Synonyms: | AKOS BBS-00005838;4-CHLOROPYRIMIDIN-2-AMINE;2-PYRIMIDINAMINE, 4-CHLORO-;2-AMINO-4-CHLOROPYRIMIDINE;CHLORO-ISO-CYTOSINE;2-Pyrimidinamine, 4-chloro- (9CI);2-AMINO-4-CHLOROPYRIMIDINE, 98+%;2-Amino-4-chloropyri |
| CAS: | 3993-78-0 |
| MF: | C4H4ClN3 |
| MW: | 129.55 |
| EINECS: | |
| Product Categories: | Bases & Related Reagents;Heterocycles;Nucleotides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles;Amines;Pyrazines, Pyrimidines & Pyridazines;Heterocyclic Compounds;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Heterocycle-Pyrimidine series;chloropyrimidin;PYRIMIDINE;APIs & Intermediate;Pyridines, Pyrimidines, Purines and Pteredines |
| Mol File: | 3993-78-0.mol |
| 2-Amino-4-chloropyrimidine Chemical Properties |
| Melting point | 155-160 °C (dec.) |
| Boiling point | 314.6±34.0 °C(Predicted) |
| density | 1.437±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl sulfoxide. |
| pka | 3.55±0.10(Predicted) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 3993-78-0(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-41-37/38-22 |
| Safety Statements | 26-36/37/39-36/39-60 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29335990 |
| MSDS Information |
| 2-Amino-4-chloropyrimidine Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | 2-Amino-4-chloropyrimidine is a substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. |
| Uses | Substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide. |
| Purification Methods | It has also been purified by sublimation in a vacuum and recrystrallisation from H2O. [Hilbert & Johnson J Am Chem Soc 52 1155 1930, Beilstein 24 H 80, 25 III/IV 2117.] |
| 2-Amino-4-chloropyrimidine Preparation Products And Raw materials |
| Raw materials | Phosphorus oxychloride-->Chlorosulfonic acid-->Isocytosine |
| Preparation Products | 2-AMINO-4-METHOXYPYRIMIDINE-->4-Pyrimidinecarbonitrile, 2-amino- (9CI)-->5-bromo-4-chloropyrimidin-2-amine |
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