Product

4-Chloro-N-methylpiperidine

CAS No.：5570-77-4

Other grades of this product :

4-Chloro-N-methylpiperidine Basic information

Product Name:	4-Chloro-N-methylpiperidine
Synonyms:	4-chloro-1-methyl-piperidin;4-CHLORO-N-METHYL PIPERIDINE;(2Z)-2-(1-amino-3-methyl-2-benzimidazolylidene)-2-cyanoacetic acid ethyl ester;4-chloro-n-methylpiperidine Hydrochloride CAS 5570-77-4;4-CHLORO-1-METHYLPIPERIDINE;1-METHYL-4-CHLORO-PIPERIDINE;N-METHYL-4-CHLORO PIPERIDINE;N- METHYL 4 CHLORO PIPERIDINE BASE
CAS:	5570-77-4
MF:	C6H12ClN
MW:	133.62
EINECS:	226-942-4
Product Categories:	Heterocyclic Compounds;PHARMACEUTICAL INTERMEDIATES;5570-77-4
Mol File:	5570-77-4.mol

4-Chloro-N-methylpiperidine Chemical Properties

Melting point	160-165°C
Boiling point	162°C(lit.)
density	1.02
vapor pressure	3.493hPa at 25℃
refractive index	1.4670-1.4710
Fp	48 °C
storage temp.	Inert atmosphere,Room Temperature
form	clear liquid to slightly cloudy liquid
pka	7.88±0.10(Predicted)
color	Colorless to Light yellow to Light orange
Water Solubility	1.533g/L at 29℃
InChIKey	MYGXGCCFTPKWIH-UHFFFAOYSA-N
LogP	1.318 at 25℃
CAS DataBase Reference	5570-77-4(CAS DataBase Reference)
EPA Substance Registry System	Piperidine, 4-chloro-1-methyl- (5570-77-4)

Safety Information

Hazard Codes	Xi,C
Risk Statements	10-34-36/38
Safety Statements	22-24/25-45-36/37/39-26-36-16
RIDADR	1993
HazardClass	3
PackingGroup	III
HS Code	29333990

MSDS Information

4-Chloro-N-methylpiperidine Usage And Synthesis

Chemical Properties	Clear colorless liquid
Uses	4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.
Flammability and Explosibility	Notclassified

4-Chloro-N-methylpiperidine Preparation Products And Raw materials

Raw materials	Thionyl chloride-->4-Hydroxypiperidine-->1-Methyl-4-piperidone
Preparation Products	4-Chloro-1-methylpiperidine hydrochloride-->1-(1-Methyl-4-piperidinyl)piperazine-->1-Methylpiperdin-4-ylmagnesium chloride, 0.50 M in THF-->4-Chloropiperidine

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