FMOC-12-AMINODODECANOIC ACID

FMOC-12-AMINODODECANOIC ACID
  • CAS No.:128917-74-8
Other grades of this product :
FMOC-12-AMINODODECANOIC ACID Basic information
Product Name:FMOC-12-AMINODODECANOIC ACID
Synonyms:N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINODODECANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINOLAURIC ACID;N-(9-FLUORENYLMETHYLOXYCARBONYL)-12-AMINO-DODECANOIC ACID;FMOC-12-ADO-OH;FMOC-12-AMINODODECANOIC ACID;FMOC-12-AMINOLAURIC ACID;FMOC-NH-(CH2)11-COOH;12-(FMOC-AMINO)DODECANOIC ACID
CAS:128917-74-8
MF:C27H35NO4
MW:437.57
EINECS:
Product Categories:Amino Acids
Mol File:128917-74-8.mol
FMOC-12-AMINODODECANOIC ACID Chemical Properties
Melting point 102 °C
Boiling point 628.8±28.0 °C(Predicted)
density 1.119±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka4.78±0.10(Predicted)
BRN 9593537
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
FMOC-12-AMINODODECANOIC ACID Usage And Synthesis
DescriptionFmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical PropertiesWhite to off-white powder
FMOC-12-AMINODODECANOIC ACID Preparation Products And Raw materials
Raw materials12-AMINODODECANOIC ACID-->N-(9-Fluorenylmethoxycarbonyloxy)succinimide-->9-Fluorenylmethyl chloroformate

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