ACETYLTHIOCHOLINE IODIDE

ACETYLTHIOCHOLINE IODIDE
  • CAS No.:1866-15-5
Other grades of this product :
ACETYLTHIOCHOLINE IODIDE Basic information
Product Name:ACETYLTHIOCHOLINE IODIDE
Synonyms:Acetylthiocholinjodid;S-ACETYLTHIOCHOLINE IODIDE extrapure AR substrate for acetylcholinesterase;S-Acetylthiocholine iodide,98%;acetylthiocholinediiodide;Ethanaminium,2-(acetylthio)-N,N,N-trimethyl-,iodide;S-[2-(trimethyl-lambda5-azanyl)ethyl] ethanethioate hydroiodide;s-acetylthio-choliniodide;(2-MERCAPTOETHYL)TRIMETHYLAMMONIMUM IODIDE ACETATE
CAS:1866-15-5
MF:C7H16INOS
MW:289.18
EINECS:217-474-1
Product Categories:susbtrate;Substrates;Ammonium Iodides (Quaternary);Quaternary Ammonium Compounds
Mol File:1866-15-5.mol
ACETYLTHIOCHOLINE IODIDE Chemical Properties
Melting point 205-210 °C(lit.)
density 1.4885 (estimate)
storage temp. 2-8°C
solubility H2O: 100 mg/mL
form powder
color white
Sensitive Light Sensitive & Hygroscopic
BRN 3916578
InChIKeyNTBLZMAMTZXLBP-UHFFFAOYSA-M
CAS DataBase Reference1866-15-5(CAS DataBase Reference)
EPA Substance Registry SystemEthanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide (1866-15-5)
Safety Information
Hazard Codes T,Xi
Risk Statements 21-25-36/37/38
Safety Statements 26-36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS FZ9865000
3-8-10
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29309099
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
ACETYLTHIOCHOLINE IODIDE Usage And Synthesis
Chemical Propertieswhite crystalline powder
UsesA nAChR agonist and substrate of acetylcholinesterase
UsesAcetylthiocholine iodide has been used as a substrate in the preparation of acetylcholine esterase (AChE) assay working solution for AChE activity assay. It has also been used as a component in phosphate buffer (PB) for cholinesterase assay.
UsesSubstrate for the colorimetric determination of acetylcholinesterase activity.
Purification MethodsRecrystallise the iodide from propan-1-ol (or iso-PrOH, or EtOH/Et2O) until almost colourless and dry it in a vacuum desiccator over P2O5. Its solubility in H2O is 1% w/v. A 0.075M (21.7mg/mL) solution in 0.1M phosphate buffer pH 8.0 is stable for 10-15 days if kept refrigerated. Store it away from light. It is commercially available as a 1% solution in H2O. [Ellman et al. Biochemical Pharmacology 7, 88 1961, IR: Hansen Acta Chem Scand 13 151 1959, 11 537 1957, Clin Chim Acta 2 316 1957, Ivin Zh Obshch Khim 22 267 1952, Beilstein 4 III 726, 4 IV 1585.]

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