N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine

N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
  • CAS No.:179552-74-0
Other grades of this product :
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Basic information
Product Name:N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine
Synonyms:N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinamine;(3-chloro-4-fluoro-phenyl)-(7-methoxy-6-nitro-quinazolin-4-yl)-amine;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-;Afatinib Impurity 137;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitro-4-Quinazolinam...;N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;179552-74-0
CAS:179552-74-0
MF:C15H10ClFN4O3
MW:348.72
EINECS:207-985-8
Product Categories:
Mol File:179552-74-0.mol
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Chemical Properties
Boiling point 515.5±50.0 °C(Predicted)
density 1.529±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka5.07±0.70(Predicted)
Safety Information
MSDS Information
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Usage And Synthesis
UsesN-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine Preparation Products And Raw materials
Preparation ProductsN-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine

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