4-Chloro-3-nitrobenzoyl chloride

CAS No.：38818-50-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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4-Chloro-3-nitrobenzoyl chloride Basic information

Product Name:	4-Chloro-3-nitrobenzoyl chloride
Synonyms:	Benzoyl chloride, 4-chloro-3-nitro-;4-CHLORO-3-NITROBENZOYL CHLORIDE;AKOS B022432;ART-CHEM-BB B022432;4-Chloro-3-nitrobenzoic acid chloride;3-Nitro-4-chlorobenzoic acid chloride;4-Chloro-3-nitrobenzoyl chloride,96%;4-Chloro-3-nitrobenzoyl chloride,98%
CAS:	38818-50-7
MF:	C7H3Cl2NO3
MW:	220.01
EINECS:	254-133-6
Product Categories:	Acid Halides;Carbonyl Compounds;Organic Building Blocks;Aromatics;Miscellaneous Reagents
Mol File:	38818-50-7.mol

4-Chloro-3-nitrobenzoyl chloride Chemical Properties

Melting point	47-54 °C(lit.)
Boiling point	301.7±22.0 °C(Predicted)
density	1.5741 (rough estimate)
refractive index	1.6140 (estimate)
Fp	230 °F
storage temp.	Inert atmosphere,2-8°C
Stability:	Stable, but may be air and moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	38818-50-7(CAS DataBase Reference)
NIST Chemistry Reference	4-Chloro-3-nitrobenzoyl chloride(38818-50-7)

Safety Information

Hazard Codes	C
Risk Statements	34-21
Safety Statements	26-27-36/37/39-45-25
RIDADR	UN 3261 8/PG 2
WGK Germany	3
HazardClass	8
PackingGroup	III
HS Code	29163900

MSDS Information

Provider	Language
4-Chloro-3-nitrobenzoyl chloride	English
SigmaAldrich	English
ACROS	English

4-Chloro-3-nitrobenzoyl chloride Usage And Synthesis

Chemical Properties	powder or crystals
Uses	4-Chloro-3-nitrobenzoyl chloride may be employed as acylation reagent for the Friedel-Crafts acylation of activated benzenes such as anisole, veratrole and 1,4-dimethoxybenzene. It may be employed for the synthesis of 4-chloro-4-methoxy-3-nitrobenzophenone. It may be employed as acylation reagent for the acylation reaction of the deactivated amines (2- aminopyrimidine, aminopyrazine).
General Description	4-Chloro-3-nitrobenzoyl chloride is an acid halide.

4-Chloro-3-nitrobenzoyl chloride Preparation Products And Raw materials

Preparation Products

4-Chloro-3-nitrobenzoic acid-->4-CHLORO-3-NITROBENZAMIDE-->(4-AMINO-3-NITROPHENYL)(4-FLUOROPHENYL)METHANONE-->4-CHLORO-3-NITROBENZOPHENONE

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