VALERIC ANHYDRIDE

CAS No.：2082-59-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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VALERIC ANHYDRIDE Basic information

Product Name:	VALERIC ANHYDRIDE
Synonyms:	VALERIC ANHYDRIDE;Pentanoic acid, anhydride;Pentanoicacid,anhydride;pentanoicacidanhydride;PENTANOIC ANHYDRIDE;N-PENTANOIC ANHYDRIDE;N-VALERIC ANHYDRIDE;VALERIC ANHYDRIDE 98%
CAS:	2082-59-9
MF:	C10H18O3
MW:	186.25
EINECS:	218-212-9
Product Categories:
Mol File:	2082-59-9.mol

VALERIC ANHYDRIDE Chemical Properties

Melting point	-56 °C (lit.)
Boiling point	228-230 °C (lit.)
density	0.944 g/mL at 20 °C (lit.)
vapor pressure	5Pa at 25℃
refractive index	n20/D 1.421(lit.)
Fp	214 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
color	Clear colorless to yellow
BRN	1770130
InChIKey	DUCKXCGALKOSJF-UHFFFAOYSA-N
LogP	3.33 at 25℃
CAS DataBase Reference	2082-59-9(CAS DataBase Reference)
EPA Substance Registry System	Pentanoic acid, anhydride (2082-59-9)

Safety Information

Hazard Codes	C
Risk Statements	34
Safety Statements	26-36/37/39-45
RIDADR	UN 3265 8/PG 3
WGK Germany	3
HazardClass	8
PackingGroup	III
HS Code	29159000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

VALERIC ANHYDRIDE Usage And Synthesis

Chemical Properties	clear colorless to yellow liquid
Uses	Valeric Anhydride is used in the synthesis of non-imadazole histamine H3-antagonists. Also used in the preparation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
Uses	Valeric anhydride can be used as a reactant to synthesize: Alkyl 9-nitrocamptothecin esters by the esterification reaction. Modified bismuth metal-organic frameworks (Bi-MOFs). O-acylated chitosan nanofibers (CSNFs) for potential usage in biomaterials and food packaging.
Flammability and Explosibility	Nonflammable

VALERIC ANHYDRIDE Preparation Products And Raw materials

Raw materials	Pentanoic acid, anhydride with acetic acid-->SODIUM VALERATE-->Valeric acid-->Acetyl chloride-->1-Pentanol-->Butyric Acid-->Benzene-->Acetic anhydride-->Valeryl chloride-->Oxalyl chloride
Preparation Products	PERFLUOROPENTANOIC ACID-->Formic acid-->Adipic acid

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