2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID

2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
  • CAS No.:352535-96-7

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID Basic information
Product Name:2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID
Synonyms:AKOS BRN-0988;2-FLUORO-5-(TRIFLUOROMETHYL)BENZENEBORONIC ACID;2-FLUORO-5-(TRIFLUOROMETHYL)BORONIC ACID;2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID;2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORON&;2-FLUOROPYRIDINE-5-(TRIFLUOROMERHYL)PHENYLBORONIC ACID;Boronic acid, [2-fluoro-5-(trifluoromethyl)phenyl]- (9CI);2-Fluoro-5-(trifluoromethyl)benzeneboronic acid 98%
CAS:352535-96-7
MF:C7H5BF4O2
MW:207.92
EINECS:
Product Categories:Boronic Acids;Organoborons;Trifluoromethyl;Boronic acid;Boronic Acids;Boronic Acids and Derivatives;BORONICACID;blocks;BoronicAcids;FluoroCompounds;Aryl
Mol File:352535-96-7.mol
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID Chemical Properties
Melting point 104-109 °C(lit.)
Boiling point 262℃
density 1.44
Fp 113℃
storage temp. Keep Cold
solubility soluble in Methanol
form Powder
pka7.35±0.58(Predicted)
color White
CAS DataBase Reference352535-96-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
Hazard Note Irritant/Keep Cold
HazardClass IRRITANT, KEEP COLD
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID Usage And Synthesis
Chemical PropertiesOff-white Cryst
Usessuzuki reaction
UsesReactant for:
  • Functionalization via lithiation and reaction with electrophiles
  • Selective rhodium-catalyzed conjugate addition reactions
  • Preparation of inhibitors of kinesin spindle protein (KSP) for potential use as antitumor agents
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials4-Fluorobenzotrifluoride-->Hydrochloric acid-->Trimethyl borate

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