(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt

CAS No.：76204-02-9

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(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Basic information

Product Name:	(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt
Synonyms:	NEU5AC-A-4MU;NEU5AC-ALPHA-4MU SODIUM SALT;2'-(4-METHYLUMBELLIFERYL)-A-D-N-ACETYLNEURAMINIC ACID, SODIUM SALT;2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT;4-MU-NANA NA;2-(4-methylumbelliferyl)-A-D-N-*acetylneuraminic;Sodium 2-(4-methylumbelliferyl)-N-acetylneuraminate;4-methylumbelliferyl-N-acetyl-alpha-D-neuram.A.so-S.dihy.
CAS:	76204-02-9
MF:	C21H26NNaO11
MW:	491.42
EINECS:	1533716-785-6
Product Categories:	substrate;Carbohydrates & Derivatives;Fluorescent Labels & Indicators
Mol File:	76204-02-9.mol

(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Chemical Properties

Melting point	171°C dec.
storage temp.	−20°C
solubility	H₂O: 50 mg/mL, clear, very slightly yellow
form	Solid
color	White to Off-White

Safety Information

Safety Statements	24/25
WGK Germany	3
F	3-10
HS Code	29322090

MSDS Information

(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Usage And Synthesis

Description	4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.
Chemical Properties	Off-White to Yellow Solid
Uses	Used as a substrate in a fluorometric assay of neuraminidase.
Uses	(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt has been used for fluorometric assay of neuraminidase as well as fluorescent staining of sialidases in PAGE.
Biochem/physiol Actions	Substrate for fluorometric assay of neuraminidase. Used for fluorescent staining of sialidases in PAGE.

(4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Preparation Products And Raw materials

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