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| (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Basic information |
| (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Chemical Properties |
| Melting point | 171°C dec. | | storage temp. | −20°C | | solubility | H2O: 50 mg/mL, clear, very slightly yellow | | form | Solid | | color | White to Off-White |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 3-10 | | HS Code | 29322090 |
| (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Usage And Synthesis |
| Description | 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus. | | Chemical Properties | Off-White to Yellow Solid | | Uses | Used as a substrate in a fluorometric assay of neuraminidase. | | Uses | (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt has been used for fluorometric assay of neuraminidase as well as fluorescent staining of sialidases in PAGE.
| | Biochem/physiol Actions | Substrate for fluorometric assay of neuraminidase. Used for fluorescent staining of sialidases in PAGE. |
| (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt Preparation Products And Raw materials |
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