3-Fluoropyridine-4-carboxylic acid

CAS No.：393-53-3

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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3-Fluoropyridine-4-carboxylic acid Basic information

Product Name:	3-Fluoropyridine-4-carboxylic acid
Synonyms:	3-FLUOROPYRIDINE-4-CARBOXYLIC ACID;3-FLUOROISONICOTINIC ACID;3-FLUORO-4-PYRIDINECARBOXYLIC ACID;3-Fluoropyridine-4-carboxylic acid mono hydrate;3-Fluoroisonicotinic;3-FLUORONICOTINIC ACID;3-FLUOROISONICOTINIC ACID MONO HYDRATE;3-Fluoro-4-pyridinecarboxylic
CAS:	393-53-3
MF:	C6H4FNO2
MW:	141.1
EINECS:	639-266-3
Product Categories:	Fluorine series;Morpholines/Thiomorpholines;blocks;Carboxes;Building Blocks;Fluorinated;FluoroCompounds;Pyridines;Pyridine;Pyridine series
Mol File:	393-53-3.mol

3-Fluoropyridine-4-carboxylic acid Chemical Properties

Melting point	251-254°C (dec.)
Boiling point	360.0±22.0 °C(Predicted)
density	1.419±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	2.85±0.10(Predicted)
BRN	383678
InChIKey	POLXLLIQWDBJMD-UHFFFAOYSA-N
CAS DataBase Reference	393-53-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,F
Risk Statements	36/37/38-10
Safety Statements	26-36-16
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933399990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

3-Fluoropyridine-4-carboxylic acid Usage And Synthesis

3-Fluoropyridine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

2-Amino-5-nitro-4-picoline-->3-Fluoro-4-methylpyridine-->2-Hydroxy-4-methyl-3-nitropyridine-->2-Amino-3-nitro-4-picoline-->CARBON DIOXIDE-->2-Hydroxy-4-methyl-5-nitropyridine-->2-Chloro-4-methyl-3-nitropyridine-->2-Chloro-4-methyl-5-nitropyridine-->3-Amino-4-methylpyridine-->3-Fluoropyridine

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