4-Methylcatechol

4-Methylcatechol
  • CAS No.:452-86-8
Other grades of this product :
4-Methylcatechol Basic information
Product Name:4-Methylcatechol
Synonyms:2-Hydroxy-4-methylphenol;4-Methyl-1,2-benzenediol (4-methylpyrocatechol);4-Methyl-1,2-dihydroxybenzene;4-methyl-2-benzenediol;4-methyl-benzene-1,2-diol;4-methyl-pyrocatecho;PARA-METHYLCATECHOL;3,4-DIHYDROXYTOLUENE / 4-METHYLCATECHOL
CAS:452-86-8
MF:C7H8O2
MW:124.14
EINECS:207-214-5
Product Categories:Pharmaceutical Intermediate;Aromatic Hydrocarbons (substituted) & Derivatives
Mol File:452-86-8.mol
4-Methylcatechol Chemical Properties
Melting point 67-69 °C (lit.)
Boiling point 251 °C (lit.)
density 1.129 g/mL at 25 °C (lit.)
refractive index 1.5425 (estimate)
Fp 140 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Powder or Chunks
pka9.91±0.10(Predicted)
color White to brown
Specific Gravity1.129
Water Solubility soluble
BRN 636512
InChIKeyZBCATMYQYDCTIZ-UHFFFAOYSA-N
CAS DataBase Reference452-86-8(CAS DataBase Reference)
NIST Chemistry Reference1,2-Benzenediol, 4-methyl-(452-86-8)
EPA Substance Registry System1,2-Benzenediol, 4-methyl- (452-86-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 2811
WGK Germany 3
RTECS UX1915000
HazardClass 6.1(b)
PackingGroup III
HS Code 29072990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-Methylcatechol Usage And Synthesis
Chemical Propertieswhite to brown powder or chunks
Uses4-Methylcatechol is used to synthesize antimicrobial, antioxidant. It also acts as effective inhibitor. It can be used to produce 4-bromo-5-methyl-pyrocatechol. It Increases Brain-Derived Neurotrophic Factor Content and mRNA Expression in Cultured Brain Cells and in Rat Brain In Vivo.
DefinitionChEBI: A methylcatechol having a single methyl substituent at the 4-position. It has been isolated from Picea abies.
Purification MethodsCrystallise the catechol from *C6H6. The purity is checked by TLC. Crystallise it from high-boiling pet ether and distil it in a vacuum. [Beilstein 6 IV 5878.]

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