2-Methylbenzimidazole
2-Methylbenzimidazole
  • CAS No.:615-15-6
Other grades of this product :
2-Methylbenzimidazole Basic information
Product Name:2-Methylbenzimidazole
Synonyms:2-METHYL-1H-BENZO[D]IMIDAZOLE;2-METHYL-1H-BENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;AKOS 90363;1H-2-Methylbenzimidazol;1H-2-Methylbenzimidazole;2-methyl-1h-benzimidazol;2-methyl-benzimidazol
CAS:615-15-6
MF:C8H8N2
MW:132.16
EINECS:210-411-9
Product Categories:Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Benzimidazoles;BENZIMIDAZOLE;Building Blocks;Heterocyclic Building Blocks
Mol File:615-15-6.mol
2-Methylbenzimidazole Chemical Properties
Melting point 175-177 °C (lit.)
Boiling point 234.08°C (rough estimate)
density 1.1083 (rough estimate)
refractive index 1.6013 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
pka6.19(at 25℃)
color Light beige to brown
Water Solubility slightly soluble
BRN 112264
InChIKeyLDZYRENCLPUXAX-UHFFFAOYSA-N
CAS DataBase Reference615-15-6(CAS DataBase Reference)
NIST Chemistry Reference1H-benzimidazole, 2-methyl-(615-15-6)
EPA Substance Registry System1H-Benzimidazole, 2-methyl- (615-15-6)
Safety Information
Hazard Codes Xn
Risk Statements 22-37/38-41-20/21/22
Safety Statements 26-39-45-44
WGK Germany 3
RTECS DD9100000
TSCA Yes
HS Code 29339990
MSDS Information
ProviderLanguage
2-Methyl-1H-benzo[d]imidazole English
ACROS English
SigmaAldrich English
ALFA English
2-Methylbenzimidazole Usage And Synthesis
Chemical Propertieslight beige to brown crystalline powder
Uses
  • 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
  • It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
  • It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
  • 2-Methylbenzimidazole also exhibits corrosion inhibition.
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 26, p. 1163, 1989 DOI: 10.1002/jhet.5570260447Chemical and Pharmaceutical Bulletin, 17, p. 1153, 1969 DOI: 10.1248/cpb.17.1153
Safety ProfilePoison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

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