Other grades of this product :
| FMOC-L-Leucine Basic information |
| FMOC-L-Leucine Chemical Properties |
| Melting point | 152-156 °C(lit.) | | Boiling point | 486.83°C (rough estimate) | | alpha | -26 º (c=1,DMF 24 ºC) | | density | 1.2107 (rough estimate) | | refractive index | -25 ° (C=1, DMF) | | storage temp. | Store below +30°C. | | solubility | DMF (Slightly), DMSO (Slightly) | | pka | 3.91±0.21(Predicted) | | form | Solid | | color | White to Off-White | | optical activity | [α]20/D 25±2°, c = 1% in DMF | | BRN | 2178254 | | Stability: | Hygroscopic | | InChIKey | CBPJQFCAFFNICX-IBGZPJMESA-N | | CAS DataBase Reference | 35661-60-0(CAS DataBase Reference) |
| FMOC-L-Leucine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs. | | Uses | Fmoc-Leu-OH can be used as a reactant to synthesize:- Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.
- A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.
- Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.
- Coumaroyl dipeptide amide that can be used for cosmetic applications.
| | Biological Activity | Anti-inflammatory agent; increases intracellular Ca 2+ levels. | | Biochem/physiol Actions | PPARγ ligand that induces insulin sensitization, but not adipogenesis. |
| FMOC-L-Leucine Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye