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| NICOTINIC ACID HYDRAZIDE Basic information |
| NICOTINIC ACID HYDRAZIDE Chemical Properties |
| Melting point | 159-161 °C(lit.) | | Boiling point | 251.97°C (rough estimate) | | density | 1.2620 (rough estimate) | | refractive index | 1.6910 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | H2O: soluble50mg/mL | | form | Fine Needle-Like Crystalline Powder | | pka | 11.43±0.10(Predicted) | | color | White to off-white | | Water Solubility | Soluble in alcohol, water. | | BRN | 119299 | | InChIKey | KFUSANSHCADHNJ-UHFFFAOYSA-N | | CAS DataBase Reference | 553-53-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-26-36/37/39 | | RIDADR | UN2811 | | WGK Germany | 3 | | RTECS | QT1750000 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29280000 | | Toxicity | LD50 intravenous in mouse: 180mg/kg |
| NICOTINIC ACID HYDRAZIDE Usage And Synthesis |
| Chemical Properties | WHITE TO OFF-WHITE FINE NEEDLE-LIKE CRYST. POWDER | | Uses | An Impurity of Isoniazid (I821450), potent antitubercular agent against M. tuberculosis.
| | Uses | Nicotinic hydrazide was used in hydrazone library formation. It was used to study the oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase. | | Biochem/physiol Actions | Nicotinic hydrazide is an inhibitor of peroxidase enzyme. It forms solid metal complexes having strong biological activity. | | Purification Methods | Crystallise it from aqueous EtOH or *benzene. [Beilstein 22 III/IV 439, 22/2 V 121.] |
| NICOTINIC ACID HYDRAZIDE Preparation Products And Raw materials |
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