Other grades of this product :
| Product Name: | Tosyl azide | | Synonyms: | Tosyl azide, 30% w/w in toluene;Tosyl azide (75% in ethyl acetate);p-Toluenesulfonazide solution;p-Toluenesulfonyl azide solution11-15 % (w/w) in Toluene,
≥ 99% (HPLC);4-methylbenzene-1-sulfonyl azide;p-Toluenesulfonyl azide, 99%, 25% in Ethyl acetate;4-methyl-benzenesulfonylazid;Benzenesulfonylazide,4-methyl- | | CAS: | 941-55-9 | | MF: | C7H7N3O2S | | MW: | 197.21 | | EINECS: | 213-381-5 | | Product Categories: | bc0001 | | Mol File: | 941-55-9.mol |
| Tosyl azide Chemical Properties |
| Tosyl azide Usage And Synthesis |
| Description | Tosyl azide is a reagent used in organic synthesis. It is prepared by the reaction of tosyl chloride with sodium azide in aqueous acetone.
| | Applications | Tosyl azide is utilized for the introduction of diazo and azide functional groups. Moreover, it is used as a nitrene and a substrate for [3+2] cycloaddition reactions.
| | Safety | Tosyl azide is a very volatile chemical that should be carefully stored and handled.
| | Chemical Properties | Colorless to slight yellow liquid | | Uses | Used for the introduction of azide and diazo functional groups. It is also used as a nitrene source and as a substrate for [3+2] cycloaddition reactions. | | Uses | 4-Methylbenzenesulfonyl Azide can be used to target Bcl-2 family proteins to potentially treat cancer. | | Uses | p-Toluenesulfonyl azide solution can be employed as a reagent along with alkyne, and amine in the three-component coupling reaction for the synthesis of N-sulfonylamidines in presence of copper catalyst.It can also be used in the synthesis of N-sulfonyl-1,2,3-triazoles by azide-alkyne cycloaddition reaction in the presence of copper catalyst. | | Synthesis Reference(s) | Synthetic Communications, 17, p. 1015, 1987 DOI: 10.1080/00397918708063962Tetrahedron Letters, 28, p. 5091, 1987 DOI: 10.1016/S0040-4039(00)95598-9 |
| Tosyl azide Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye