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| 4-Phenylbutanol Basic information |
| 4-Phenylbutanol Chemical Properties |
| Boiling point | 140-142 °C14 mm Hg(lit.) | | density | 0.984 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.521(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform | | form | Liquid | | pka | 15.13±0.10(Predicted) | | color | Clear colorless | | BRN | 2042122 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | LDZLXQFDGRCELX-UHFFFAOYSA-N | | CAS DataBase Reference | 3360-41-6(CAS DataBase Reference) | | NIST Chemistry Reference | Benzenebutanol(3360-41-6) | | EPA Substance Registry System | Benzenebutanol (3360-41-6) |
| 4-Phenylbutanol Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases. | | Uses | 4-Phenyl-1-butanol was used in synthesis of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. | | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 31, p. 2607, 1983 DOI: 10.1248/cpb.31.2607Journal of the American Chemical Society, 73, p. 124, 1951 DOI: 10.1021/ja01145a045 | | General Description | 4-Phenyl-1-butanol is oxidized by ceric ammonium nitrate in acetonitrile to afford 2-phenyltetrahydrofuran. It undergoes cyclization in presence of phosphoric acid at high temperature to yield tetralin. |
| 4-Phenylbutanol Preparation Products And Raw materials |
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